EVpedia: A community web portal for extracellular vesicles research

Dae Kyum Kim, Jaewook Lee, Sae Rom Kim, Dong Sic Choi, Yae Jin Yoon, Ji Hyun Kim, Gyeongyun Go, Dinh Nhung, Kahye Hong, Su Chul Jang, Si Hyun Kim, Kyong Su Park, Oh Youn Kim, Hyun Taek Park, Ji Hye Seo, Elena Aikawa, Monika Baj-Krzyworzeka, Bas W M Van Balkom, Mattias Belting, Lionel BlancVincent Bond, Antonella Bongiovanni, Francesc E. Borràs, Luc Buée, Edit I. Buzás, Lesley Cheng, Aled Clayton, Emanuele Cocucci, Charles S. Dela Cruz, Dominic M. Desiderio, Dolores Di Vizio, Karin Ekström, Juan M. Falcon-Perez, Chris Gardiner, Bernd Giebel, David W. Greening, Julia Christina Gross, Dwijendra Gupta, An Hendrix, Andrew F. Hill, Michelle M. Hill, Esther Nolte-'T Hoen, Do Won Hwang, Jameel Inal, Medicharla V. Jagannadham, Muthuvel Jayachandran, Young Koo Jee, Malene Jørgensen, Kwang Pyo Kim, Yoon Keun Kim, Thomas Kislinger, Cecilia Lässer, Dong Soo Lee, Hakmo Lee, Johannes Van Leeuwen, Thomas Lener, Ming Lin Liu, Jan Lötvall, Antonio Marcilla, Suresh Mathivanan, Andreas Möller, Jess Morhayim, Francois Mullier, Irina Nazarenko, Rienk Nieuwland, Diana N. Nunes, Ken Pang, Jaesung Park, Tushar Patel, Gabriella Pocsfalvi, Hernando Del Portillo, Ulrich Putz, Marcel I. Ramirez, Marcio L. Rodrigues, Tae Young Roh, Felix Royo, Susmita Sahoo, Raymond Schiffelers, Shivani Sharma, Pia Siljander, Richard J. Simpson, Carolina Soekmadji, Philip Stahl, Allan Stensballe, Ewa Stepień, Hidetoshi Tahara, Arne Trummer, Hadi Valadi, Laura J. Vella, Sun Nyunt Wai, Kenneth Witwer, Maria Yánez-Mó, Hyewon Youn, Reinhard Zeidler, Yong Song Gho

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Résumé

Motivation: Extracellular vesicles (EVs) are spherical bilayered proteolipids, harboring various bioactive molecules. Due to the complexity of the vesicular nomenclatures and components, online searches for EV-related publications and vesicular components are currently challenging. Results: We present an improved version of EVpedia, a public database for EVs research. This community web portal contains a database of publications and vesicular components, identification of orthologous vesicular components, bioinformatic tools and a personalized function. EVpedia includes 6879 publications, 172 080 vesicular components from 263 high-throughput datasets, and has been accessed more than 65 000 times from more than 750 cities. In addition, about 350 members from 73 international research groups have participated in developing EVpedia. This free web-based database might serve as a useful resource to stimulate the emerging field of EV research. Availability and implementation: The web site was implemented in PHP, Java, MySQL and Apache, and is freely available at http://evpedia.info.

langue originaleAnglais
Pages (de - à)933-939
Nombre de pages7
journalBioinformatics
Volume31
Numéro de publication6
Les DOIs
Etat de la publicationPublié - 15 mars 2015

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