DualChip® microarray as a new tool in cancer research

Jean-Pierre Gillet, F. De Longueville, J. Remacle

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Résumé

Over the last 5 years, the emergence of gene expression profiling using high-density DNA microarrays led to a better understanding of tumor development and identified new prognostic markers. However, high-density microarrays failed to leap from the researcher's bench to the clinical practice due to their cost, data management and lack of standardization. DualChip® low-density DNA microarrays were developed as a new flexible tool that is able to reliably quantify the expression of a limited number of genes of clinical relevance. This review will illustrate how DualChip technology can be applied to tumor diagnosis and tumor-acquired drug resistance.
langue originaleAnglais
Pages (de - à)295-306
Nombre de pages12
journalExpert Review of Molecular Diagnostics
Volume6
Numéro de publication3
Les DOIs
Etat de la publicationPublié - 1 janv. 2006

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