Résumé
The cyclization of several substituted 5-phenyl-pent-4-en-1-ols with selenium electrophiles along some mechanistic considerations is discussed. In particular, an efficient diastereoselective synthesis of a 2,3,5,6-tetrasubstitued tetrahydropyran is reported. These findings open an interesting approach: the use of chiral selenium electrophiles for cyclization of chiral substrates. The cyclized products are useful starting material for the synthesis of D- or L-aryl C-glycosides.
langue originale | Anglais |
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Pages (de - à) | 681-690 |
Nombre de pages | 10 |
journal | Heterocycles |
Volume | 63 |
Numéro de publication | 3 |
Etat de la publication | Publié - 1 mars 2004 |