Close-packed array of gold nanoparticles and Sum Frequency Generation spectroscopy in total internal reflection: A platform for studying biomolecules and biosensors

G. Tourillon; L. Dreesen; C. Volcke; Y. Sartenaer; P.A. Thiry; A. Peremans

doi:10.1007/s10853-009-3572-y

Close-packed array of gold nanoparticles and Sum Frequency Generation spectroscopy in total internal reflection: A platform for studying biomolecules and biosensors

G. Tourillon, L. Dreesen, C. Volcke, Y. Sartenaer, P.A. Thiry, A. Peremans

Résultats de recherche: Contribution à un journal/une revue › Article › Revue par des pairs

Résumé

An approach is introduced for studying the adsorption and recognition mechanisms of biomolecules, without using any markers. We show for the first time, that the sum frequency generation spectroscopy performed in the total internal reflection (TIR-SFG) geometry, combined with a regular close-packed array of gold nanoparticles allows to probe with a high sensitivity the changes in conformation and orientation induced by the recognition process of avidin by biocytin. This approach represents a new platform with potential use in biosensors, diagnostics and bioactive layers. © 2009 Springer Science+Business Media, LLC.

langue originale	Anglais
Pages (de - à)	6805-6810
Nombre de pages	6
journal	Journal of Materials Science
Volume	44
Numéro de publication	24
Les DOIs	https://doi.org/10.1007/s10853-009-3572-y
Etat de la publication	Publié - 1 janv. 2009

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10.1007/s10853-009-3572-y

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abstract = "An approach is introduced for studying the adsorption and recognition mechanisms of biomolecules, without using any markers. We show for the first time, that the sum frequency generation spectroscopy performed in the total internal reflection (TIR-SFG) geometry, combined with a regular close-packed array of gold nanoparticles allows to probe with a high sensitivity the changes in conformation and orientation induced by the recognition process of avidin by biocytin. This approach represents a new platform with potential use in biosensors, diagnostics and bioactive layers. {\textcopyright} 2009 Springer Science+Business Media, LLC.",

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Close-packed array of gold nanoparticles and Sum Frequency Generation spectroscopy in total internal reflection: A platform for studying biomolecules and biosensors. / Tourillon, G.; Dreesen, L.; Volcke, C. et al.
Dans: Journal of Materials Science, Vol 44, Numéro 24, 01.01.2009, p. 6805-6810.

Résultats de recherche: Contribution à un journal/une revue › Article › Revue par des pairs

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T1 - Close-packed array of gold nanoparticles and Sum Frequency Generation spectroscopy in total internal reflection: A platform for studying biomolecules and biosensors

AU - Tourillon, G.

AU - Dreesen, L.

AU - Volcke, C.

AU - Sartenaer, Y.

AU - Thiry, P.A.

AU - Peremans, A.

PY - 2009/1/1

Y1 - 2009/1/1

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AB - An approach is introduced for studying the adsorption and recognition mechanisms of biomolecules, without using any markers. We show for the first time, that the sum frequency generation spectroscopy performed in the total internal reflection (TIR-SFG) geometry, combined with a regular close-packed array of gold nanoparticles allows to probe with a high sensitivity the changes in conformation and orientation induced by the recognition process of avidin by biocytin. This approach represents a new platform with potential use in biosensors, diagnostics and bioactive layers. © 2009 Springer Science+Business Media, LLC.

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KW - Biosensors

KW - sum frequency generation spectroscopy

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Close-packed array of gold nanoparticles and Sum Frequency Generation spectroscopy in total internal reflection: A platform for studying biomolecules and biosensors

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