Circadian preference modulates the neural substrate of conflict processing across the day

Christina Schmidt, Philippe Peigneux, Yves Leclercq, Virginie Sterpenich, Gilles Vandewalle, Christophe Phillips, Pierre Berthomier, Christian Berthomier, Gilberte Tinguely, Steffen Gais, Manuel Schabus, Martin Desseilles, Thanh Dang-Vu, Eric Salmon, Christian Degueldre, Evelyne Balteau, André Luxen, Christian Cajochen, Pierre Maquet, Fabienne Collette

Résultats de recherche: Contribution à un journal/une revueArticle

Résumé

Human morning and evening chronotypes differ in their preferred timing for sleep and wakefulness, as well as in optimal daytime periods to cope with cognitive challenges. Recent evidence suggests that these preferences are not a simple by-product of socio-professional timing constraints, but can be driven by inter-individual differences in the expression of circadian and homeostatic sleep-wake promoting signals. Chronotypes thus constitute a unique tool to access the interplay between those processes under normally entrained day-night conditions, and to investigate how they impinge onto higher cognitive control processes. Using functional magnetic resonance imaging (fMRI), we assessed the influence of chronotype and time-of-day on conflict processing-related cerebral activity throughout a normal waking day. Sixteen morning and 15 evening types were recorded at two individually adapted time points (1.5 versus 10.5 hours spent awake) while performing the Stroop paradigm. Results show that interference-related hemodynamic responses are maintained or even increased in evening types from the subjective morning to the subjective evening in a set of brain areas playing a pivotal role in successful inhibitory functioning, whereas they decreased in morning types under the same conditions. Furthermore, during the evening hours, activity in a posterior hypothalamic region putatively involved in sleep-wake regulation correlated in a chronotype-specific manner with slow wave activity at the beginning of the night, an index of accumulated homeostatic sleep pressure. These results shed light into the cerebral mechanisms underlying inter-individual differences of higher-order cognitive state maintenance under normally entrained day-night conditions.
langue originaleAnglais
Pages (de - à)e29658
journalPLoS Genetics
Volume7
Numéro de publication1
Les DOIs
étatPublié - 2012

Empreinte digitale

sleep
Sleep
substrate
Individuality
Posterior Hypothalamus
Stroop Test
Wakefulness
process control
hemodynamics
magnetic resonance imaging
brain
Hemodynamics
Maintenance
Magnetic Resonance Imaging
Pressure
Conflict (Psychology)
conflict
Brain

Citer ceci

Schmidt, C., Peigneux, P., Leclercq, Y., Sterpenich, V., Vandewalle, G., Phillips, C., ... Collette, F. (2012). Circadian preference modulates the neural substrate of conflict processing across the day. PLoS Genetics, 7(1), e29658. https://doi.org/10.1371/journal.pone.0029658
Schmidt, Christina ; Peigneux, Philippe ; Leclercq, Yves ; Sterpenich, Virginie ; Vandewalle, Gilles ; Phillips, Christophe ; Berthomier, Pierre ; Berthomier, Christian ; Tinguely, Gilberte ; Gais, Steffen ; Schabus, Manuel ; Desseilles, Martin ; Dang-Vu, Thanh ; Salmon, Eric ; Degueldre, Christian ; Balteau, Evelyne ; Luxen, André ; Cajochen, Christian ; Maquet, Pierre ; Collette, Fabienne. / Circadian preference modulates the neural substrate of conflict processing across the day. Dans: PLoS Genetics. 2012 ; Vol 7, Numéro 1. p. e29658.
@article{173545c05f64404b96e22e7f78bb16e8,
title = "Circadian preference modulates the neural substrate of conflict processing across the day",
abstract = "Human morning and evening chronotypes differ in their preferred timing for sleep and wakefulness, as well as in optimal daytime periods to cope with cognitive challenges. Recent evidence suggests that these preferences are not a simple by-product of socio-professional timing constraints, but can be driven by inter-individual differences in the expression of circadian and homeostatic sleep-wake promoting signals. Chronotypes thus constitute a unique tool to access the interplay between those processes under normally entrained day-night conditions, and to investigate how they impinge onto higher cognitive control processes. Using functional magnetic resonance imaging (fMRI), we assessed the influence of chronotype and time-of-day on conflict processing-related cerebral activity throughout a normal waking day. Sixteen morning and 15 evening types were recorded at two individually adapted time points (1.5 versus 10.5 hours spent awake) while performing the Stroop paradigm. Results show that interference-related hemodynamic responses are maintained or even increased in evening types from the subjective morning to the subjective evening in a set of brain areas playing a pivotal role in successful inhibitory functioning, whereas they decreased in morning types under the same conditions. Furthermore, during the evening hours, activity in a posterior hypothalamic region putatively involved in sleep-wake regulation correlated in a chronotype-specific manner with slow wave activity at the beginning of the night, an index of accumulated homeostatic sleep pressure. These results shed light into the cerebral mechanisms underlying inter-individual differences of higher-order cognitive state maintenance under normally entrained day-night conditions.",
keywords = "Adult, Biological Markers, Brain Mapping, Chronobiology Phenomena, Circadian Rhythm, Conflict (Psychology), Electrophysiological Phenomena, Energy Metabolism, Female, Habits, Humans, Individuality, Magnetic Resonance Imaging, Male, Negotiating, Neurons, Sleep, Time Factors, Wakefulness, Young Adult",
author = "Christina Schmidt and Philippe Peigneux and Yves Leclercq and Virginie Sterpenich and Gilles Vandewalle and Christophe Phillips and Pierre Berthomier and Christian Berthomier and Gilberte Tinguely and Steffen Gais and Manuel Schabus and Martin Desseilles and Thanh Dang-Vu and Eric Salmon and Christian Degueldre and Evelyne Balteau and Andr{\'e} Luxen and Christian Cajochen and Pierre Maquet and Fabienne Collette",
year = "2012",
doi = "10.1371/journal.pone.0029658",
language = "English",
volume = "7",
pages = "e29658",
journal = "PLoS Genetics",
issn = "1553-7390",
publisher = "Public Library of Science",
number = "1",

}

Schmidt, C, Peigneux, P, Leclercq, Y, Sterpenich, V, Vandewalle, G, Phillips, C, Berthomier, P, Berthomier, C, Tinguely, G, Gais, S, Schabus, M, Desseilles, M, Dang-Vu, T, Salmon, E, Degueldre, C, Balteau, E, Luxen, A, Cajochen, C, Maquet, P & Collette, F 2012, 'Circadian preference modulates the neural substrate of conflict processing across the day', PLoS Genetics, VOL. 7, Numéro 1, p. e29658. https://doi.org/10.1371/journal.pone.0029658

Circadian preference modulates the neural substrate of conflict processing across the day. / Schmidt, Christina; Peigneux, Philippe; Leclercq, Yves; Sterpenich, Virginie; Vandewalle, Gilles; Phillips, Christophe; Berthomier, Pierre; Berthomier, Christian; Tinguely, Gilberte; Gais, Steffen; Schabus, Manuel; Desseilles, Martin; Dang-Vu, Thanh; Salmon, Eric; Degueldre, Christian; Balteau, Evelyne; Luxen, André; Cajochen, Christian; Maquet, Pierre; Collette, Fabienne.

Dans: PLoS Genetics, Vol 7, Numéro 1, 2012, p. e29658.

Résultats de recherche: Contribution à un journal/une revueArticle

TY - JOUR

T1 - Circadian preference modulates the neural substrate of conflict processing across the day

AU - Schmidt, Christina

AU - Peigneux, Philippe

AU - Leclercq, Yves

AU - Sterpenich, Virginie

AU - Vandewalle, Gilles

AU - Phillips, Christophe

AU - Berthomier, Pierre

AU - Berthomier, Christian

AU - Tinguely, Gilberte

AU - Gais, Steffen

AU - Schabus, Manuel

AU - Desseilles, Martin

AU - Dang-Vu, Thanh

AU - Salmon, Eric

AU - Degueldre, Christian

AU - Balteau, Evelyne

AU - Luxen, André

AU - Cajochen, Christian

AU - Maquet, Pierre

AU - Collette, Fabienne

PY - 2012

Y1 - 2012

N2 - Human morning and evening chronotypes differ in their preferred timing for sleep and wakefulness, as well as in optimal daytime periods to cope with cognitive challenges. Recent evidence suggests that these preferences are not a simple by-product of socio-professional timing constraints, but can be driven by inter-individual differences in the expression of circadian and homeostatic sleep-wake promoting signals. Chronotypes thus constitute a unique tool to access the interplay between those processes under normally entrained day-night conditions, and to investigate how they impinge onto higher cognitive control processes. Using functional magnetic resonance imaging (fMRI), we assessed the influence of chronotype and time-of-day on conflict processing-related cerebral activity throughout a normal waking day. Sixteen morning and 15 evening types were recorded at two individually adapted time points (1.5 versus 10.5 hours spent awake) while performing the Stroop paradigm. Results show that interference-related hemodynamic responses are maintained or even increased in evening types from the subjective morning to the subjective evening in a set of brain areas playing a pivotal role in successful inhibitory functioning, whereas they decreased in morning types under the same conditions. Furthermore, during the evening hours, activity in a posterior hypothalamic region putatively involved in sleep-wake regulation correlated in a chronotype-specific manner with slow wave activity at the beginning of the night, an index of accumulated homeostatic sleep pressure. These results shed light into the cerebral mechanisms underlying inter-individual differences of higher-order cognitive state maintenance under normally entrained day-night conditions.

AB - Human morning and evening chronotypes differ in their preferred timing for sleep and wakefulness, as well as in optimal daytime periods to cope with cognitive challenges. Recent evidence suggests that these preferences are not a simple by-product of socio-professional timing constraints, but can be driven by inter-individual differences in the expression of circadian and homeostatic sleep-wake promoting signals. Chronotypes thus constitute a unique tool to access the interplay between those processes under normally entrained day-night conditions, and to investigate how they impinge onto higher cognitive control processes. Using functional magnetic resonance imaging (fMRI), we assessed the influence of chronotype and time-of-day on conflict processing-related cerebral activity throughout a normal waking day. Sixteen morning and 15 evening types were recorded at two individually adapted time points (1.5 versus 10.5 hours spent awake) while performing the Stroop paradigm. Results show that interference-related hemodynamic responses are maintained or even increased in evening types from the subjective morning to the subjective evening in a set of brain areas playing a pivotal role in successful inhibitory functioning, whereas they decreased in morning types under the same conditions. Furthermore, during the evening hours, activity in a posterior hypothalamic region putatively involved in sleep-wake regulation correlated in a chronotype-specific manner with slow wave activity at the beginning of the night, an index of accumulated homeostatic sleep pressure. These results shed light into the cerebral mechanisms underlying inter-individual differences of higher-order cognitive state maintenance under normally entrained day-night conditions.

KW - Adult

KW - Biological Markers

KW - Brain Mapping

KW - Chronobiology Phenomena

KW - Circadian Rhythm

KW - Conflict (Psychology)

KW - Electrophysiological Phenomena

KW - Energy Metabolism

KW - Female

KW - Habits

KW - Humans

KW - Individuality

KW - Magnetic Resonance Imaging

KW - Male

KW - Negotiating

KW - Neurons

KW - Sleep

KW - Time Factors

KW - Wakefulness

KW - Young Adult

U2 - 10.1371/journal.pone.0029658

DO - 10.1371/journal.pone.0029658

M3 - Article

C2 - 22238632

VL - 7

SP - e29658

JO - PLoS Genetics

JF - PLoS Genetics

SN - 1553-7390

IS - 1

ER -

Schmidt C, Peigneux P, Leclercq Y, Sterpenich V, Vandewalle G, Phillips C et al. Circadian preference modulates the neural substrate of conflict processing across the day. PLoS Genetics. 2012;7(1):e29658. https://doi.org/10.1371/journal.pone.0029658