Résumé
Stress response to fluctuating environments often implies a time-consuming reprogramming of gene expression. In bacteria, the so-called bet hedging strategy, which promotes phenotypic stochasticity within a cell population, is the only fast stress response described so far 1. Here, we show that Caulobacter crescentus asymmetrical cell division allows an immediate bimodal response to a toxic metals-rich environment by allocating specific defence strategies to morphologically and functionally distinct siblings. In this context, a motile swarmer cell favours negative chemotaxis to flee from a copper source, whereas a sessile stalked sibling engages a ready-to-use PcoAB copper homeostasis system, providing evidence of a prompt stress response through intrinsic bacterial dimorphism.
langue originale | Anglais |
---|---|
Numéro d'article | 16098 |
journal | Nature Microbiology |
Volume | 1 |
Numéro de publication | 9 |
Les DOIs | |
Etat de la publication | Publié - 4 juil. 2016 |
Empreinte digitale
Examiner les sujets de recherche de « Caulobacter crescentus intrinsic dimorphism provides a prompt bimodal response to copper stress ». Ensemble, ils forment une empreinte digitale unique.Équipement
-
Morphologie - Imagerie
Cecchet, F. (!!Manager) & Renard, H.-F. (!!Manager)
Plateforme technologique Morphologie, imagerieEquipement/installations: Plateforme technolgique