Brucellosis in wildlife in Africa: a systematic review and meta-analysis

Gregory Simpson, Peter N Thompson, Claude Saegerman, Tanguy Marcotty, Jean-Jacques Letesson, Xavier De Bolle, Jacques Godfroid

Résultats de recherche: Contribution à un journal/une revueArticleRevue par des pairs

6 Téléchargements (Pure)


This study aimed to consolidate current knowledge of wildlife brucellosis in Africa and to analyse available predictors of infection. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines were followed. Information on species, test used, test results, area, rainfall, livestock and wildlife contact and year of study were extracted. This systematic review revealed 42 prevalence studies, nine disease control articles and six articles on epidemiology. Brucella abortus, Brucella melitensis, Brucella inopinata and Brucella suis were reported in wildlife. The prevalence studies revealed serological evidence of brucellosis in buffalo, antelope (positive in 14/28 species), carnivores (4/12) and other species (7/20) over the last five decades. Buffalo populations were more likely to be infected and had a higher seroprevalence than other species; the pooled seroprevalence was 13.7% (95% CI 10.3-17.3%) in buffalo, 7.1% (95% CI 1.1-15.5%) in carnivores and 2.1% (95% CI 0.1-4.9%) in antelope. Wildlife in high rainfall areas (≥ 800 mm) were more likely to be infected, and infected populations showed higher seroprevalence in high rainfall areas and in studies published after 2000. Domestic animal contact was associated with increased seroprevalence in antelope and carnivore species, but not in buffalo, supporting the hypothesis that buffalo may be a reservoir species.

langue originaleAnglais
Numéro d'article5960
Pages (de - à)5960
journalScientific Reports
Numéro de publication1
Les DOIs
Etat de la publicationPublié - déc. 2021

Empreinte digitale

Examiner les sujets de recherche de « Brucellosis in wildlife in Africa: a systematic review and meta-analysis ». Ensemble, ils forment une empreinte digitale unique.

Contient cette citation