Biologically Active Heteroglycoclusters Constructed on a Pillar[5]arene-Containing [2]Rotaxane Scaffold

Stéphane P. Vincent; Kévin Buffet; Iwona Nierengarten; Anne Imberty; Jean François Nierengarten

doi:10.1002/chem.201504110

Biologically Active Heteroglycoclusters Constructed on a Pillar[5]arene-Containing [2]Rotaxane Scaffold

Stéphane P. Vincent, Kévin Buffet, Iwona Nierengarten, Anne Imberty, Jean François Nierengarten

Unite de recherche en chimie organique

Résultats de recherche: Contribution à un journal/une revue › Article › Revue par des pairs

Résumé

A synthetic approach combining recent concepts for the preparation of multifunctional nanomolecules (click chemistry on multifunctional scaffolds) with supramolecular chemistry (self-assembly to prepare rotaxanes) gave easy access to a large variety of sophisticated [2]rotaxane heteroglycoclusters. Specifically, compounds combining galactose and fucose have been prepared to target the two bacterial lectins (LecA and LecB) from the opportunistic pathogen Pseudomonas aeruginosa.

langue originale	Anglais
Pages (de - à)	88-92
Nombre de pages	5
journal	Chemistry: A European Journal
Volume	22
Numéro de publication	1
Les DOIs	https://doi.org/10.1002/chem.201504110
Etat de la publication	Publié - 4 janv. 2016

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10.1002/chem.201504110

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Vincent_et_al_2015_Chemistry_A_European_Journal
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title = "Biologically Active Heteroglycoclusters Constructed on a Pillar[5]arene-Containing [2]Rotaxane Scaffold",

abstract = "A synthetic approach combining recent concepts for the preparation of multifunctional nanomolecules (click chemistry on multifunctional scaffolds) with supramolecular chemistry (self-assembly to prepare rotaxanes) gave easy access to a large variety of sophisticated [2]rotaxane heteroglycoclusters. Specifically, compounds combining galactose and fucose have been prepared to target the two bacterial lectins (LecA and LecB) from the opportunistic pathogen Pseudomonas aeruginosa.",

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author = "Vincent, {St{\'e}phane P.} and K{\'e}vin Buffet and Iwona Nierengarten and Anne Imberty and Nierengarten, {Jean Fran{\c c}ois}",

year = "2016",

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doi = "10.1002/chem.201504110",

language = "English",

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AU - Imberty, Anne

AU - Nierengarten, Jean François

PY - 2016/1/4

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Biologically Active Heteroglycoclusters Constructed on a Pillar[5]arene-Containing [2]Rotaxane Scaffold

Résumé

Accès au document

Autres fichiers et liens

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Équipement

Physico-chimie et caractérisation (PC2)

Spectrométrie de masse (MASUN)

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