Asymmetric dihydroxylation of C,C double bonds using catalytic amounts of osmium tetroxide, selenides, and air

A. Krief, C. Colaux-Castillo

Résultats de recherche: Contribution à un journal/une revueArticleRevue par des pairs

Résumé

Selenides, selenoxides, osmium tetroxide, and potassium osmate dihydrate are in equilibrium in aqueous tert-butanol containing potassium carbonate. We took advantage of this feature to withdraw the equilibrium in each of the two directions to produce allylalcohols from allylselenides and diols from olefins. The latter reaction performed in the presence of catalytic amounts of Cinchona alkaloids and osmium tetroxide allows the enantioselective dihydroxylation of C,C double bonds.
langue originaleAnglais
Pages (de - à)107-113
Nombre de pages7
journalPure and Applied Chemistry
Volume74
Numéro de publication1
Etat de la publicationPublié - 1 janv. 2002

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