TY - JOUR
T1 - An efficient synthesis of GDP-hexanolamine, a key tool for the purification of fucosyltransferases
AU - Vincent, Stéphane P.
AU - Gastinel, Louis N.
PY - 2002/6/5
Y1 - 2002/6/5
N2 - A new efficient synthesis of GDP-hexanolamine from hexanolamine is reported with an overall yield of 71%. The pyrophosphate formation, the key step of this preparation, was achieved through a sequential GMP activation procedure based on polytrifluoroacetylation of GMP followed by activation of the phosphate group by 1-methylimidazole. © 2002 Published by Elsevier Science Ltd.
AB - A new efficient synthesis of GDP-hexanolamine from hexanolamine is reported with an overall yield of 71%. The pyrophosphate formation, the key step of this preparation, was achieved through a sequential GMP activation procedure based on polytrifluoroacetylation of GMP followed by activation of the phosphate group by 1-methylimidazole. © 2002 Published by Elsevier Science Ltd.
KW - GDP-hexanolamine
KW - Glycosyltransferase
KW - Pyrophosphate synthesis
UR - http://www.scopus.com/inward/record.url?scp=0037024307&partnerID=8YFLogxK
U2 - 10.1016/S0008-6215(02)00105-2
DO - 10.1016/S0008-6215(02)00105-2
M3 - Article
C2 - 12039545
SN - 0008-6215
VL - 337
SP - 1039
EP - 1042
JO - Carbohydrate Research
JF - Carbohydrate Research
IS - 11
ER -