A spatio-temporal model for spontaneous thrombus formation in cerebral aneurysms

O. Malaspinas, A. Turjman, D. Ribeiro de Sousa, G. Garcia-Cardena, Martine Raes, P. T T Nguyen, Y. Zhang, G. Courbebaisse, C. Lelubre, K. Zouaoui Boudjeltia, B. Chopard

Résultats de recherche: Contribution à un journal/une revueArticleRevue par des pairs

Résumé

We propose a new numerical model to describe thrombus formation in cerebral aneurysms. This model combines CFD simulations with a set of bio-mechanical processes identified as being the most important to describe the phenomena at a large space and time scales. The hypotheses of the model are based on in vitro experiments and clinical observations. We document that we can reproduce very well the shape and volume of patient specific thrombus segmented in giant aneurysms.

langue originaleAnglais
Pages (de - à)68-76
Nombre de pages9
journalJournal of Theoretical Biology
Volume394
Les DOIs
Etat de la publicationPublié - 7 avr. 2016

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