A simple synthesis of APM ([p-(N-acrylamino)-phenyl]mercuric chloride), a useful tool for the analysis of thiolated biomolecules

V Lemau de Talancé, F Bauer, D Hermand, S P Vincent

Résultats de recherche: Contribution à un journal/une revueArticle

Résumé

This study describes two novel synthetic procedures to prepare APM, a useful tool for the analysis and the purification of thiolated biomolecules. The methods developed are technically simple and robust and allowed the first full characterization of pure APM. Moreover, the efficacy of APM, as a biochemical tool, was demonstrated by analysis of tRNA thiolation by APM-PAGE.
langue originaleAnglais
Pages (de - à)7265-7
Nombre de pages3
journalBioorganic & Medicinal Chemistry Letters
Volume21
Numéro de publication24
Les DOIs
Etat de la publicationPublié - 2011

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