17O NMR Study of Diamagnetic and Paramagnetic Lanthanide(III)-DOTA Complexes in Aqueous Solution.

Luca Fusaro, Michel. Luhmer

Résultats de recherche: Contribution à un journal/une revueArticle

Résumé

The complexes between the polyaminocarboxylate DOTA ligand and the whole series of stable lanthanide(III) metal ions, except Gd3+, were studied in aq. soln. by 17O NMR. For all of the paramagnetic systems, the 17O NMR signals of both the nonchelating (O1) and chelating (O2) O atoms could be detected, and for some of them, the signals of both the SAP and TSAP (TSAP') conformational isomers were also obsd. Line width data anal. reveals that signal broadening is not dominated by paramagnetic relaxation enhancement, as it was believed to be. Quadrupole relaxation and, for some complexes, chem. exchange between the SAP and TSAP isomers are the major contributions to the 17O NMR line width at 25°. Besides, the Fermi contact and pseudocontact contributions to the obsd. lanthanide-induced shifts could be extd. The 17O hyperfine coupling consts. detd. for O2 in the SAP and TSAP isomers are similar to each other and to the values reported for several Gd(III) complexes comprising fast-exchanging ligands. Probably 17O NMR should prove to should be useful for the study of highly paramagnetic Gd(III) complexes of nonlabile ligands. [on SciFinder(R)]
langueAnglais
Pages8717-8722
Nombre de pages6
journalInorganic Chemistry
Volume53
Numéro16
Les DOIs
étatPublié - 2014
Modification externeOui

Empreinte digitale

aqueous solutions
nuclear magnetic resonance
Lanthanoid Series Elements
Nuclear magnetic resonance
isomers
ligands
Isomers
Ligands
Linewidth
exchanging
electric contacts
metal ions
quadrupoles
augmentation
shift
atoms
Chelation
Metal ions
Atoms

mots-clés

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    abstract = "The complexes between the polyaminocarboxylate DOTA ligand and the whole series of stable lanthanide(III) metal ions, except Gd3+, were studied in aq. soln. by 17O NMR. For all of the paramagnetic systems, the 17O NMR signals of both the nonchelating (O1) and chelating (O2) O atoms could be detected, and for some of them, the signals of both the SAP and TSAP (TSAP\{textquoteleft}) conformational isomers were also obsd. Line width data anal. reveals that signal broadening is not dominated by paramagnetic relaxation enhancement, as it was believed to be. Quadrupole relaxation and, for some complexes, chem. exchange between the SAP and TSAP isomers are the major contributions to the 17O NMR line width at 25°. Besides, the Fermi contact and pseudocontact contributions to the obsd. lanthanide-induced shifts could be extd. The 17O hyperfine coupling consts. detd. for O2 in the SAP and TSAP isomers are similar to each other and to the values reported for several Gd(III) complexes comprising fast-exchanging ligands. Probably 17O NMR should prove to should be useful for the study of highly paramagnetic Gd(III) complexes of nonlabile ligands. [on SciFinder(R)]",
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    17O NMR Study of Diamagnetic and Paramagnetic Lanthanide(III)-DOTA Complexes in Aqueous Solution. / Fusaro, Luca; Luhmer, Michel.

    Dans: Inorganic Chemistry, Vol 53, Numéro 16, 2014, p. 8717-8722.

    Résultats de recherche: Contribution à un journal/une revueArticle

    TY - JOUR

    T1 - 17O NMR Study of Diamagnetic and Paramagnetic Lanthanide(III)-DOTA Complexes in Aqueous Solution.

    AU - Fusaro,Luca

    AU - Luhmer,Michel.

    N1 - M1 - Copyright (C) 2014 American Chemical Society (ACS). All Rights Reserved. CAPLUS AN 2014:1260612(Journal; Online Computer File)

    PY - 2014

    Y1 - 2014

    N2 - The complexes between the polyaminocarboxylate DOTA ligand and the whole series of stable lanthanide(III) metal ions, except Gd3+, were studied in aq. soln. by 17O NMR. For all of the paramagnetic systems, the 17O NMR signals of both the nonchelating (O1) and chelating (O2) O atoms could be detected, and for some of them, the signals of both the SAP and TSAP (TSAP') conformational isomers were also obsd. Line width data anal. reveals that signal broadening is not dominated by paramagnetic relaxation enhancement, as it was believed to be. Quadrupole relaxation and, for some complexes, chem. exchange between the SAP and TSAP isomers are the major contributions to the 17O NMR line width at 25°. Besides, the Fermi contact and pseudocontact contributions to the obsd. lanthanide-induced shifts could be extd. The 17O hyperfine coupling consts. detd. for O2 in the SAP and TSAP isomers are similar to each other and to the values reported for several Gd(III) complexes comprising fast-exchanging ligands. Probably 17O NMR should prove to should be useful for the study of highly paramagnetic Gd(III) complexes of nonlabile ligands. [on SciFinder(R)]

    AB - The complexes between the polyaminocarboxylate DOTA ligand and the whole series of stable lanthanide(III) metal ions, except Gd3+, were studied in aq. soln. by 17O NMR. For all of the paramagnetic systems, the 17O NMR signals of both the nonchelating (O1) and chelating (O2) O atoms could be detected, and for some of them, the signals of both the SAP and TSAP (TSAP') conformational isomers were also obsd. Line width data anal. reveals that signal broadening is not dominated by paramagnetic relaxation enhancement, as it was believed to be. Quadrupole relaxation and, for some complexes, chem. exchange between the SAP and TSAP isomers are the major contributions to the 17O NMR line width at 25°. Besides, the Fermi contact and pseudocontact contributions to the obsd. lanthanide-induced shifts could be extd. The 17O hyperfine coupling consts. detd. for O2 in the SAP and TSAP isomers are similar to each other and to the values reported for several Gd(III) complexes comprising fast-exchanging ligands. Probably 17O NMR should prove to should be useful for the study of highly paramagnetic Gd(III) complexes of nonlabile ligands. [on SciFinder(R)]

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