Olivier Toussaint

  • 5552 Citations
  • 37 h-Index
1990 …2019
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Résultat de recherche 1990 2019

Filtre
Article
2019

Gender- and age-dependencies of oxidative stress, as detected based on the steady state concentrations of different biomarkers in the MARK-AGE study

Pinchuk, I., Weber, D., Kochlik, B., Stuetz, W., Toussaint, O., Debacq-Chainiaux, F., Dollé, M. E. T., Jansen, E. H. J. M., Gonos, E. S., Sikora, E., Breusing, N., Gradinaru, D., Sindlinger, T., Moreno-Villanueva, M., Bürkle, A., Grune, T. & Lichtenberg, D., 1 juin 2019, Dans : Redox Biology. 24, p. 101204 101204.

Résultats de recherche: Contribution à un journal/une revueArticle

Accès ouvert
Oxidative stress
Biomarkers
Malondialdehyde
Oxidative Stress
Antioxidants
2018

A guide to nanosafety testing: Considerations on cytotoxicity testing in different cell models

Riebeling, C., Piret, J. P., Trouiller, B., Nelissen, I., Saout, C., Toussaint, O. & Haase, A., 1 avr. 2018, Dans : NanoImpact. 10, p. 1-10 10 p.

Résultats de recherche: Contribution à un journal/une revueArticle

Cytotoxicity
Nanoparticles
Assays
Testing
Dendritic Cells

Protection against Tetanus and Diphtheria in Europe: The impact of age, gender and country of origin based on data from the MARK-AGE Study

Weinberger, B., Keller, M., Putzer, C., Breitenberger, D., Koller, B., Fiegl, S., Moreno-Villanueva, M., Bernhardt, J., Franceschi, C., Voutetakis, K., Gonos, E. S., Hurme, M., Sikora, E., Toussaint, O., Debacq-Chainiaux, F., Grune, T., Breusing, N., Bürkle, A. & Grubeck-Loebenstein, B., 1 mai 2018, Dans : Experimental Gerontology. 105, p. 109-112 4 p.

Résultats de recherche: Contribution à un journal/une revueArticle

Diphtheria
Tetanus
Antibodies
Vaccination
Greece

Role of Prion protein in premature senescence of human fibroblasts

Boilan, E., Winant, V., Dumortier, É., Elmoualij, B., Quatresooz, P., Osiewacz, H. D., Debacq-Chainiaux, F. & Toussaint, O., 1 mars 2018, Dans : Mechanisms of Ageing and Development. 170, p. 106-113 8 p.

Résultats de recherche: Contribution à un journal/une revueArticle

Fibroblasts
Copper
Protein Isoforms
Galactosidases
Copper Sulfate

Zinc-Induced Metallothionein in Centenarian Offspring from a Large European Population: The MARK-AGE Project

Giacconi, R., Costarelli, L., Piacenza, F., Basso, A., Bürkle, A., Moreno-Villanueva, M., Grune, T., Weber, D., Stuetz, W., Gonos, E. S., Schön, C., Grubeck-Loebenstein, B., Sikora, E., Toussaint, O., Debacq-Chainiaux, F., Franceschi, C., Hervonen, A., Slagboom, E., Ciccarone, F., Zampieri, M. & 6 autres, Caiafa, P., Jansen, E., Dollé, M. E. T., Breusing, N., Mocchegiani, E. & Malavolta, M., 9 mai 2018, Dans : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 73, 6, p. 745-753 9 p.

Résultats de recherche: Contribution à un journal/une revueArticle

Metallothionein
Zinc
Population
Blood Cells
Homeostasis
2017

Associations between Specific Redox Biomarkers and Age in a Large European Cohort: The MARK-AGE Project

Weber, D., Stuetz, W., Toussaint, O., Debacq-Chainiaux, F., Dollé, M., Jansen, E., Gonos, E. S., Franceschi, C., Sikora, E., Hervonen, A., Breusing, N., Sindlinger, T., Moreno-Villanueva, M., Bürkle, A. & Grune, T., 2017, Dans : Oxidative Medicine and Cellular Longevity. 2017, 1401452.

Résultats de recherche: Contribution à un journal/une revueArticle

Biomarkers
Oxidation-Reduction
Cysteine
Oxidative stress
Tocopherols
2016
2 Downloads (Pure)

Age-dependent expression of DNMT1 and DNMT3B in PBMCs from a large European population enrolled in the MARK-AGE study

Ciccarone, F., Malavolta, M., Calabrese, R., Guastafierro, T., Bacalini, M. G., Reale, A., Franceschi, C., Capri, M., Hervonen, A., Hurme, M., Grubeck-Loebenstein, B., Koller, B., Bernhardt, J., Schӧn, C., Slagboom, P. E., Toussaint, O., Sikora, E., Gonos, E. S., Breusing, N., Grune, T. & 7 autres, Jansen, E., Dollé, M., Moreno-Villanueva, M., Sindlinger, T., Bürkle, A., Zampieri, M. & Caiafa, P., 1 août 2016, Dans : Aging Cell. 15, 4, p. 755-765 11 p.

Résultats de recherche: Contribution à un journal/une revueArticle

Accès ouvert
File
Methyltransferases
DNA
Feeding Behavior
DNA Methylation
Epigenomics

Pan-European inter-laboratory studies on a panel of in vitro cytotoxicity and pro-inflammation assays for nanoparticles

Piret, J. P., Bondarenko, O. M., Boyles, M. S. P., Himly, M., Ribeiro, A. R., Benetti, F., Smal, C., Lima, B., Potthoff, A., Simion, M., Dumortier, E., Leite, P. E. C., Balottin, L. B., Granjeiro, J. M., Ivask, A., Kahru, A., Radauer-Preiml, I., Tischler, U., Duschl, A., Saout, C. & 6 autres, Anguissola, S., Haase, A., Jacobs, A., Nelissen, I., Misra, S. K. & Toussaint, O., 10 déc. 2016, (Accepté/sous presse) Dans : Archives of Toxicology. p. 1-16 16 p.

Résultats de recherche: Contribution à un journal/une revueArticle

Cytotoxicity
Nanoparticles
Assays
Inflammation
Caspase 7
2015
Silicon carbide
silicon carbides
Acute
rats
Rats
1 Downloads (Pure)

MARK-AGE biomarkers of ageing

Bürkle, A., Moreno-Villanueva, M., Bernhard, J., Blasco, M., Zondag, G., Hoeijmakers, J. H. J., Toussaint, O., Grubeck-Loebenstein, B., Mocchegiani, E., Collino, S., Gonos, E. S., Sikora, E., Gradinaru, D., Dollé, M., Salmon, M., Kristensen, P., Griffiths, H. R., Libert, C., Grune, T., Breusing, N. & 10 autres, Simm, A., Franceschi, C., Capri, M., Talbot, D., Caiafa, P., Friguet, B., Slagboom, P. E., Hervonen, A., Hurme, M. & Aspinall, R., 2015, Dans : Mechanisms of Ageing and Development. 151, p. 2-12

Résultats de recherche: Contribution à un journal/une revueArticle

Biomarkers
Literature
Cross-Sectional Studies
Population
1 Downloads (Pure)

MARK-AGE population: From the human model to new insights

Capri, M., Moreno-Villanueva, M., Cevenini, E., Pini, E., Scurti, M., Borelli, V., Palmas, M. G., Zoli, M., Schön, C., Siepelmeyer, A., Bernhardt, J., Fiegl, S., Zondag, G., de Craen, A. J. M., Hervonen, A., Hurme, M., Sikora, E., Gonos, E. S., Voutetakis, K., Toussaint, O. & 4 autres, Debacq-Chainiaux, F., Grubeck-Loebenstein, B., Bürkle, A. & Franceschi, C., 1 nov. 2015, Dans : Mechanisms of Ageing and Development. 151, p. 13-17 5 p.

Résultats de recherche: Contribution à un journal/une revueArticle

Accès ouvert

Novel ageing-biomarker discovery using data-intensive technologies

Griffiths, H. R., Augustyniak, E. M., Bennett, S. J., Debacq-Chainiaux, F., Dunston, C. R., Kristensen, P., Melchjorsen, C. J., Navarrete, S. A., Simm, A. & Toussaint, O., 2015, Dans : Mechanisms of Ageing and Development. 151, p. 114-121 8 p.

Résultats de recherche: Contribution à un journal/une revueArticle

Accès ouvert
Biomarkers
Technology
Cell Aging
Proteomics
T-Lymphocytes
9 Downloads (Pure)

Quality control data of physiological and immunological biomarkers measured in serum and plasma

Jansen, E., Beekhof, P., Cremers, J., Weinberger, B., Fiegl, S., Toussaint, O., Bernhard, J., Gonos, E., Capri, M., Franceschi, C., Sikora, E., Moreno-Villanueva, M., Breusing, N., Grune, T., Bürkle, A. & Dollé, M. E. T., 30 janv. 2015, Dans : Mechanisms of Ageing and Development. 151, p. 54-59 6 p.

Résultats de recherche: Contribution à un journal/une revueArticle

Accès ouvert
File
Quality Control
Biomarkers
Serum
Hemolysis
Hyperlipidemias
14 Downloads (Pure)
Accès ouvert
File
Serum Globulins
Nanoparticles
nanoparticles
Nanomedicine
Medical nanotechnology
53 Downloads (Pure)
Accès ouvert
File
silicon carbides
carbides
lungs
rats
neutrophils
2014
Nanostructures
Platelets
Nanostructured materials
Blood Platelets
Carbon

Can TiC nanoparticles produce toxicity in oral administration to rats?

Laloy, J., Lozano Garcia, O., Alpan, L., Mejia Mendoza, J. H., Toussaint, O., Masereel, B., Dogne, J-M. & Lucas, S., 12 mai 2014, Dans : Toxicology Reports. 1, p. 172-187 16 p.

Résultats de recherche: Contribution à un journal/une revueArticle

Nanoparticles
Minerals
Oral Administration
Toxicity
Rats
2 Downloads (Pure)

Combating inflammaging through a Mediterranean whole diet approach: The NU-AGE project's conceptual framework and design

Santoro, A., Pini, E., Scurti, M., Palmas, G., Berendsen, A., Brzozowska, A., Pietruszka, B., Szczecinska, A., Cano, N., Meunier, N., de Groot, C. P. G. M., Feskens, E., Fairweather-Tait, S., Salvioli, S., Capri, M., Brigidi, P., Franceschi, C. & The NU-AGE Consortium, 1 janv. 2014, (Accepté/sous presse) Dans : Mechanisms of Ageing and Development.

Résultats de recherche: Contribution à un journal/une revueArticle

Mediterranean Diet
Metagenomics
Food
Metabolomics
Systems Biology
8 Downloads (Pure)
detachment
Pumps
pumps
X rays
evaluation

How to classify the oldest old according to their health status: A study on 1160 subjects belonging to 552 90+ Italian sib-ships characterized by familial longevity recruited within the GEHA EU Project

Cevenini, E., Cotichini, R., Stazi, M. A., Toccaceli, V., Scurti, M., Mari, V., Berardelli, M., Passarino, G., Jeune, B., Franceschi, C., Bezrukov, V., Blanché, H., Bolund, L., Christensen, K., Deiana, L., Gonos, E., Hervonen, A., Kirkwood, T. B. L., Kristensen, P., Leon, A. & 12 autres, Pelicci, P. G., Perola, M., Poulain, M., Rea, I. M., Remacle, J., Robine, J. M., Schreiber, S., Sikora, E., Slagboom, P. E., Spazzafumo, L., Toussaint, O. & Vaupel, J. W., 1 janv. 2014, Dans : Mechanisms of Ageing and Development. 134, 11-12, p. 560-569 10 p.

Résultats de recherche: Contribution à un journal/une revueArticle

Ships
Italy
Health Status
Healthy Volunteers
Survival

Impact of silver nanoparticles on haemolysis, platelet function and coagulation

Laloy, J., Minet, V., Alpan, L., Mullier, F., Beken, S., Toussaint, O., Lucas, S. & Dogne, J-M., 18 sept. 2014, Dans : Nanomaterials and Nanotechnology. 4, 9 p.

Résultats de recherche: Contribution à un journal/une revueArticle

Platelets
Hemolysis
Coagulation
Platelet Aggregation
Silver
Copper oxides
copper oxides
Toxicity
Copper
toxicity
43 Downloads (Pure)

The co-occurrence of mtDNA mutations on different oxidative phosphorylation subunits, not detected by haplogroup analysis, affects human longevity and is population specific

Raule, N., Sevini, F., Li, S., Barbieri, A., Tallaro, F., Lomartire, L., Vianello, D., Montesanto, A., Moilanen, J. S., Bezrukov, V., Blanché, H., Hervonen, A., Christensen, K., Deiana, L., Gonos, E. S., Kirkwood, T. B. L., Kristensen, P., Leon, A., Pelicci, P. G., Poulain, M. & 18 autres, Rea, I. M., Remacle, J., Robine, J. M., Schreiber, S., Sikora, E., Eline Slagboom, P., Spazzafumo, L., Antonietta Stazi, M., Toussaint, O., Vaupel, J. W., Rose, G., Majamaa, K., Perola, M., Johnson, T. E., Bolund, L., Yang, H., Passarino, G. & Franceschi, C., 2014, Dans : Aging Cell. 13, (3):401-7

Résultats de recherche: Contribution à un journal/une revueArticle

Accès ouvert
File
Oxidative Phosphorylation
Mitochondrial DNA
Mutation
Population
Genes
2013

Dose assessment of SiC nanoparticle dispersions during in vitro assays

Mejia Mendoza, J. H., Piret, J-P., Noël, F., Masereel, B., Toussaint, O. & Lucas, S., 1 janv. 2013, Dans : Journal of Nanoparticle Research. 15, 8, 15 p., 1875.

Résultats de recherche: Contribution à un journal/une revueArticle

culture media
Dispersions
Nanoparticles
Culture Media
Assays

High-resolution quantitative metabolome analysis of urine by automated flow injection NMR

Da Silva, L., Godejohann, M., Martin, F. P. J., Collino, S., Bürkle, A., Moreno-Villanueva, M., Bernhardt, J., Toussaint, O., Grubeck-Loebenstein, B., Gonos, E. S., Sikora, E., Grune, T., Breusing, N., Franceschi, C., Hervonen, A., Spraul, M. & Moco, S., 18 juin 2013, Dans : Analytical Chemistry. 85, 12, p. 5801-5809 9 p.

Résultats de recherche: Contribution à un journal/une revueArticle

Metabolism
Nuclear magnetic resonance
Metabolites
Chemical analysis
Health
particle size distribution
dosage
oxides
cultured cells
centrifuges
7 Downloads (Pure)

Role of p38MAPK and oxidative stress in copper-induced senescence

Boilan, E., Winant, V., Dumortier, E., Piret, J-P., Bonfitto, F., Osiewacz, H. D., Debacq-Chainiaux, F. & Toussaint, O., 2013, Dans : Age. 35, 6, p. 2255-71 17 p.

Résultats de recherche: Contribution à un journal/une revueArticle

Copper
Oxidative Stress
Antioxidants
Copper Sulfate
Lipofuscin

The use of PIXE for engineered nanomaterials quantification in complex matrices

Lozano Garcia, O., Toussaint, O., Dogne, J-M. & Lucas, S., 2013, Dans : Journal of Physics : Conference Series. 429, 1, 8 p., 012010.

Résultats de recherche: Contribution à un journal/une revueArticle

rats
matrices
feces
x rays
versatility
2012
toxicology
Toxicology
Sonication
stirring
Dispersions
1 Downloads (Pure)
Oxidative stress
Copper oxides
Cytotoxicity
Nanoparticles
Chemical activation
2 Downloads (Pure)
Nanoparticles
Rats
X-Rays
X rays
Lung
1 Downloads (Pure)
Caco-2 Cells
Copper oxides
Hydrodynamics
Nanoparticles
Oxides
26 Downloads (Pure)
Feces
Nanoparticles
Toxicity
Rats
Chemical analysis
Dispersions
Nanoparticles
nanoparticles
Fluids
fluids
6 Downloads (Pure)
Carbon Nanotubes
Telomerase
Dispersions
Keratinocytes
Carbon nanotubes
Nanoparticles
X-Rays
Food
X rays
Coffee
56 Downloads (Pure)

UV, stress and aging

Debacq-Chainiaux, F., Leduc, C., Verbeke, A. & Toussaint, O., 1 juil. 2012, Dans : Dermato-endocrinology. 4, 3, p. 236-40 5 p.

Résultats de recherche: Contribution à un journal/une revueArticle

Accès ouvert
File
Skin Aging
Cell Aging
Keratinocytes
Fibroblasts
Skin
1 Downloads (Pure)
Nanostructures
Nanostructured materials
Thrombin
Nanoparticles
Assays
17 Downloads (Pure)

Wheat-derived arabinoxylan oligosaccharides with prebiotic effect increase satietogenic gut peptides and reduce metabolic endotoxemia in diet-induced obese mice

Neyrinck, A. M., Van Hée, V. F., Piront, N., De Backer, F., Toussaint, O., Cani, P. D. & Delzenne, N. M., 2012, Dans : Nutrition & diabetes. 2, p. e28

Résultats de recherche: Contribution à un journal/une revueArticle

Accès ouvert
File
Obese Mice
Prebiotics
Endotoxemia
Oligosaccharides
Triticum
2011
1 Downloads (Pure)

Artefactual effects of oxygen on cell culture models of cellular senescence and stem cell biology

Toussaint, O., Weemaels, G., Debacq-Chainiaux, F., Scharffetter-Kochanek, K. & Wlaschek, M., 1 févr. 2011, Dans : Journal of Cellular Physiology. 226, 2, p. 315-321 7 p.

Résultats de recherche: Contribution à un journal/une revueArticle

Cytology
Cell Aging
Stem cells
Cell culture
Cell Biology

Design, recruitment, logistics, and data management of the GEHA (Genetics of Healthy Ageing) project

Skytthe, A., Valensin, S., Jeune, B., Cevenini, E., Balard, F., Beekman, M., Bezrukov, V., Blanche, H., Bolund, L., Broczek, K., Carru, C., Christensen, K., Christiansen, L., Collerton, J. C., Cotichini, R., de Craen, A. J. M., Dato, S., Davies, K., De Benedictis, G., Deiana, L. & 31 autres, Flachsbart, F., Gampe, J., Gilbault, C., Gonos, E. S., Haimes, E., Hervonen, A., Hurme, M. A., Janiszewska, D., Jylhä, M., Kirkwood, T. B. L., Kristensen, P., Laiho, P., Leon, A., Marchisio, A., Masciulli, R., Nebel, A., Passarino, G., Pelicci, G., Peltonen, L., Perola, M., Poulain, M., Rea, I. M., Remacle, J., Robine, J. M., Schreiber, S., Scurti, M., Sevini, F., Sikora, E., Skouteri, A., Toussaint, O. & GEHA consortium, 2011, Dans : Experimental Gerontology. 46, 11, p. 934-45 12 p.

Résultats de recherche: Contribution à un journal/une revueArticle

Information management
Logistics
Aging of materials
Siblings
Genes

Differentially abundant transcripts in PBMC of hospitalized geriatric patients with hip fracture compared to healthy aged controls

Vo, T. K. D., Godard, P., de Saint-Hubert, M., Morrhaye, G., Debacq-Chainiaux, F., Swine, C., Geenen, V., Martens, H. J. & Toussaint, O., 1 avr. 2011, Dans : Experimental Gerontology. 46, 4, p. 257-264 8 p.

Résultats de recherche: Contribution à un journal/une revueArticle

Geriatrics
Hip Fractures
Communicable Diseases
Preexisting Condition Coverage
Hospitalization
1 Downloads (Pure)

Dimethyl sulfoxide (DMSO) attenuates the inflammatory response in the in vitro intestinal Caco-2 cell model

Hollebeeck, S., Raas, T., Piront, N., Schneider, Y-J., Toussaint, O., Larondelle, Y. & During, A., 2011, Dans : Toxicology letters. 206, 3, p. 268-75 8 p.

Résultats de recherche: Contribution à un journal/une revueArticle

Caco-2 Cells
Dimethyl Sulfoxide
Cyclooxygenase 2
Interleukin-1
Prostaglandins E
toxicology
Toxicology
Poloxamer
Surface structure
Sonication
carbon nanotubes
cells
biological effects
stirring
liver
6 Downloads (Pure)

Serum IL-6 and IGF-1 improve clinical prediction of functional decline after hospitalization in older patients

De Saint-Hubert, M., Jamart, J., Morrhaye, G., Martens, H. J., Geenen, V., Duy Vo, T. K., Toussaint, O. & Swine, C., 1 avr. 2011, Dans : Aging Clinical and Experimental Research. 23, 2, p. 106-111 6 p.

Résultats de recherche: Contribution à un journal/une revueArticle

Somatomedins
Interleukin-6
Hospitalization
Biomarkers
Logistic Models
5 Downloads (Pure)

Transcriptomic biomarkers of the response of hospitalized geriatric patients admitted with heart failure. Comparison to hospitalized geriatric patients with infectious diseases or hip fracture

Vo, T. K. D., de Saint-Hubert, M., Morrhaye, G., Godard, P., Geenen, V., Martens, H. J., Debacq-Chainiaux, F., Swine, C. & Toussaint, O., 1 mars 2011, Dans : Mechanisms of Ageing and Development. 132, 3, p. 131-139 9 p.

Résultats de recherche: Contribution à un journal/une revueArticle

Hip Fractures
Geriatrics
Communicable Diseases
Healthy Volunteers
Heart Failure