Profil personnel

Présentation

Since February 2013, employed as a post-doc researcher at the COS (chimie organique de synthèse) Laboratory, Department of Chemistry, University of Namur. Involved in the development of a continuous microfluidic process for the production of hydrogen peroxide by direct synthesis with a minimalised ecological footprint. Also working on other chemistry projects, including syntheses of biologically active compounds by means of flow chemistry and other techniques. 2008 - 2013, in the framework of multi-partner projects such as CANTOL, HOPE4PD and Télévie, worked on the development, synthesis and up-scaling of small molecule enzyme inhibitors and receptor modulators for pharmaceutical purposes. Also involved in research coordination and student training. 2004 - 2007, researcher in the medicinal chemistry laboratory of 4AZA Bioscience / elbion Bioscience) in Leuven, Belgium. In collaboration with various partners, synthesis and SAR of novel heterocyclic derivatives as new immunosuppressive and anti-schizophrenic agents. 2000 - 2004, PhD student at the Chemistry Department, KULeuven, Synthesis of novel porphyrin and oligopyrrole derivatives. Some of these compounds were successfully used in analytical systems for determination of small molecules. 1996 - 2000 at the Rudjer Boskovic Institute, Zagreb, Croatia, development and synthesis of derivatives of the plant growth hormone indole-3-acetic acid (IAA), mainly as molecular probes for research on indole-binding proteins involved in IAA biosynthesis. Part of this work is described in my MSc thesis obtained from the University of Zagreb in 2000.

Domaines de compétence

Solution phase synthesis, homogenous catalysis, MW assisted synthesis, continuous flow and microreactor technology, one- and two-dimensional NMR, MS, HPLC, UV/VIS spectroscopy, freeze drying, GC, automatised flash chromatography, SAR, PD/PK analysis, young researchers training, general and specialised computer skills.

Charges externes

Sworn translator Dutch - Serbo-Croatian.

Diplômes

PhD in organic chemistry Katholieke Universiteit Leuven, Belgium, 2000 - 2004 (Prof. Wim Dehaen)

MSc in organic chemistry University of Zagreb, Croatia, 1998 - 2000 (Dr. Volker Magnus)

BSc in organic chemistry University of Zagreb, Croatia, 1990 - 1996 (Prof. Ivan Vickovic)

Présentation

Since February 2013, employed as a post-doc researcher at the COS (chimie organique de synthèse) Laboratory, Department of Chemistry, University of Namur. Involved in the development of a continuous microfluidic process for the production of hydrogen peroxide by direct synthesis with a minimalised ecological footprint. Also working on other chemistry projects, including syntheses of biologically active compounds by means of flow chemistry and other techniques. 2008 - 2013, in the framework of multi-partner projects such as CANTOL, HOPE4PD and Télévie, worked on the development, synthesis and up-scaling of small molecule enzyme inhibitors and receptor modulators for pharmaceutical purposes. Also involved in research coordination and student training. 2004 - 2007, researcher in the medicinal chemistry laboratory of 4AZA Bioscience / elbion Bioscience) in Leuven, Belgium. In collaboration with various partners, synthesis and SAR of novel heterocyclic derivatives as new immunosuppressive and anti-schizophrenic agents. 2000 - 2004, PhD student at the Chemistry Department, KULeuven, Synthesis of novel porphyrin and oligopyrrole derivatives. Some of these compounds were successfully used in analytical systems for determination of small molecules. 1996 - 2000 at the Rudjer Boskovic Institute, Zagreb, Croatia, development and synthesis of derivatives of the plant growth hormone indole-3-acetic acid (IAA), mainly as molecular probes for research on indole-binding proteins involved in IAA biosynthesis. Part of this work is described in my MSc thesis obtained from the University of Zagreb in 2000.

Domaines de compétence

Solution phase synthesis, homogenous catalysis, MW assisted synthesis, continuous flow and microreactor technology, one- and two-dimensional NMR, MS, HPLC, UV/VIS spectroscopy, freeze drying, GC, automatised flash chromatography, SAR, PD/PK analysis, young researchers training, general and specialised computer skills.

Charges externes

Sworn translator Dutch - Serbo-Croatian.

Diplômes

PhD in organic chemistry Katholieke Universiteit Leuven, Belgium, 2000 - 2004 (Prof. Wim Dehaen)

MSc in organic chemistry University of Zagreb, Croatia, 1998 - 2000 (Dr. Volker Magnus)

BSc in organic chemistry University of Zagreb, Croatia, 1990 - 1996 (Prof. Ivan Vickovic)

Qualification académique

Docteur ès sciences, Katholieke Universiteit Leuven (KUL)

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Derivatives composés chimiques
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Réseau Récente collaboration externe au niveau du pays. Découvrez tous les détails en cliquant sur les points.

Projets 2000 2017

HOPE4PD: HOPE4PD

Masereel, B., Frederick, R., Dolusic, E., Combalbert, J., Klitgaard, H., schiffmann, S. & May, H.

31/03/1130/09/13

Projet: Recherche

CANTOL: Conception et synthèse d'inhibiteurs de l'indolaminedioxygénase (IDO) pour le traitement du cancer

Masereel, B., Wouters, J., Dolusic, E., Frederick, R., Pouyez, J., Van den Eynde, B., Frère, J. M., Moser, M., Jean-Marie, B., Combalbert, J. & Stephenne, J.

1/04/0831/03/12

Projet: Recherche

Résultat de recherche 1995 2016

Flow sinteza kombretastatina A-4

Cazin, I., De Backer, L., Collin, S., Desrues, T., Dolusic, E. & Lanners, S. 22 oct. 2016

Résultats de recherche: Contribution à une conférenceRésumé

!!File
Nuclear magnetic resonance
fosbretabulin

Flow synthesis of combretastatin A-4

Cazin, I., Dolusic, E. & Lanners, S. 5 nov. 2016 p. 53 - HS P 17 1 p.

Résultats de recherche: Contribution à une conférencePoster

Accès ouvert
!!File
Nuclear magnetic resonance
fosbretabulin
Accès ouvert
!!File
Polystyrenes
Palladium
Resins
Gases
Metals
Factor XIIa
Coumarins
Structure-Activity Relationship
Enzyme Precursors
Blood Coagulation

Direct flow synthesis of H2O2 catalysed by palladium supported on sulfonated polystyrene resins

Plas, A., Dolušić, E. & Lanners, S. 17 févr. 2015 p. P209 1 p.

Résultats de recherche: Contribution à une conférencePoster

Accès ouvert
!!File
Polystyrenes
Palladium
Resins
Anthraquinones
Bleaching

Activités 1994 2016

Bioorganic & Medicinal Chemistry Letters (journal)

Dolusic, E. (Membre d'un comité de revue par les pairs)
16 sept. 2016

Activité: Révision de publication en tant que pair

Journal of Advanced Research (journal)

Dolusic, E. (Membre d'un comité de revue par les pairs)
13 juil. 2016

Activité: Révision de publication en tant que pair

Bioorganic & Medicinal Chemistry Letters (journal)

Dolusic, E. (Membre d'un comité de revue par les pairs)
29 avr. 2016

Activité: Révision de publication en tant que pair

ACS Medicinal Chemistry Letters (journal)

Dolusic, E. (Membre d'un comité de revue par les pairs)
29 avr. 2016

Activité: Révision de publication en tant que pair

FLOW CHEMISTRY WORKSHOP 2016

Dolusic, E. (Poster)
18 janv. 201619 janv. 2016

Activité: Participation ou organisation d'un événementParticipation à un atelier/workshop, un séminaire, un cours

Thèse

Presse/Médias

Le potentiel de la microfluidique

Eduard Dolusic, Steve Lanners, Adrien Dewandre & Aurélie Plas

29/04/14

1 élément de couverture média

Presse/Médias: Autre

Mladi Ogulinac u ekipi koja je na tragu lijeka protiv raka

Eduard Dolusic

24/02/12

1 élément de couverture média

Presse/Médias: Autre

USPJEH MLADOGA OGULINCA

Eduard Dolusic

24/02/12

1 élément de couverture média

Presse/Médias: Autre

Broadening TDO's base

Eduard Dolusic, Raphaël Frederick, Bernard Masereel & Johan Wouters

23/02/12

1 élément de couverture média

Presse/Médias: Commentaire d'expert

Ogulinac Eduard Dolušić nadomak otkriću lijeka protiv raka

Eduard Dolusic

23/02/12

1 élément de couverture média

Presse/Médias: Autre