Since the eighties, the biologist has a new manner of carrying out experiments: bioin-
formatics. Moreover, Internet gave the biologist the opportunity of having a direct access
to this large laboratory distributed on various sites.
Unfortunately, collaborations between these various sites are restricted to data exchange.
Few attempts exist to standardize the data format, the appearance of the site, etc. The sites
are thus heterogeneous. However, the biologist must sometimes make the sites collaborate.
He must thus manage this heterogeneity, that curbs its use of bioinformatics.
However IT solutions to manage this heterogeneity exists like the distributed systems.
Some projects emerge in order to develop distributed systems in the bioinformatics frame-
work. One of them that is called BIGRE is carried out in partnership between the University
of Brussels and the University of Namur.
This master thesis is within the scope of this project and its aim is the modeling of
various components of bioinformatics in order to oer a homogeneous user interface to the