Analysis of a mannose-6-phosphorylation defect in breast cancer cells
: causes, consequences on lysosomal functions and on cancer cell aggressiveness

    Student thesis: Master types › Master in Biomedicine Professional focus

    Abstract

    Analysis of the effect of a mutation of GNPTAB reported in BT549 cells on the lysosomal functions
    Date of Award17 Jan 2020
    Original languageEnglish
    Awarding Institution
    • University of Namur
    SupervisorMarielle Boonen (Supervisor)

    Keywords

    • Breast cancer
    • GlcNAc-1-phosphotransferase
    • Mannose-6-phosphate
    • Trafficking
    • Lysosomal acid hydrolases

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