Abstract
(Equation presented) A new access to benzhydryl-phenylureas is described. These new interesting urea derivatives were obtained by reaction of substituted benzils with substituted phenylureas under microwave irradiation. Phenylthiourea, when reacted with benzil, gave 3-phenyl-thiohydantoin. Moreover, benzylurea, as phenethylurea, gave the corresponding 3-substituted hydantoin derivatives, demonstrating that only phenylurea derivatives can result in benzhydryl-phenylureas under the applied conditions. This new reaction proved to be an easy access to substituted 1-benzhydryl-3-phenyl-ureas.
Original language | English |
---|---|
Pages (from-to) | 3599-3602 |
Number of pages | 4 |
Journal | Organic Letters |
Volume | 5 |
Issue number | 20 |
DOIs | |
Publication status | Published - 2 Oct 2003 |
Fingerprint
Dive into the research topics of 'Versatile access to benzhydryl-phenylureas through an unexpected rearrangement during microwave-enhanced synthesis of hydantoins'. Together they form a unique fingerprint.Datasets
-
CCDC 211705: Experimental Crystal Structure Determination
Lambert, D. M. (Contributor), Muccioli, G. (Contributor), Norberg, B. (Contributor), Poppitz, W. (Contributor), Poupaert, J. H. (Contributor), Scriba, G. K. E. (Contributor) & Wouters, J. (Contributor), Cambridge Crystallographic Data Centre, 1 Jan 2004
DOI: 10.5517/cc7396t, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc7396t&sid=DataCite
Dataset