Tryptophan 2,3-dioxygenase (TDO) inhibitors. 3-(2-(pyridyl)ethenyl)indoles as potential anticancer immunomodulators

Search results

• 2012

  Reversal of Tumoral Immune Resistance by Inhibition of Tryptophan 2,3-Dioxygenase (TDO): Design, Synthesis and Preclinical Evaluation of a Novel TDO Inhibitor.

  Dolušić, E., Larrieu, P., Moineaux, L., Stroobant, V., Pilotte, L., Colaux, D., Van den Eynde, B., Masereel, B., Wouters, J. & Frédérick, R., 2012, In: ChemMedChem. p. 371 1 p.

  Research output: Contribution to journal › Literature review › peer-review

• 2010

  Discovery and optimization of indole-pyridinyl-ethanones as novel inhibitors of indoleamine-2-3 dioxygenase (IDO), a promising target for anti-cancer immunotherapy.

  Frédérick, R., Blanc, S., Larrieu, P., Moineaux, L., Colette, D., Fraser, G., Stroobant, V., Pilotte, L., Colaux, D., Wouters, J., Masereel, B., Van den Eynde, B. & Dolušić, E., 2010, In: Drugs of the future. 35, suppl A, p. 181-182

  Research output: Contribution to journal › Literature review › peer-review

• Structural and enzymatic study of tryptophan 2,3-dioxgenase (TDO), a potential target in anticancer immunotherapy.

  Moineaux, L., Charlier, C., Dolušić, E., Larrieu, P., Pilotte, L., Colaux, D., Stroobant, V., Galleni, M., Masereel, B., Van den Eynde, B., Wouters, J. & Frédérick, R., 2010, In: Drugs of the future. 35, suppl A, p. 189

  Research output: Contribution to journal › Literature review › peer-review