Transient increased extracellular release of HO during establishment of UVB-induced premature senescence

C. Borlon, A. Chretien, F. Debacq-Chainiaux, O. Toussaint

Research output: Contribution to journalArticlepeer-review

Abstract

In this work, we found that extracellular release of HO is 1.5- to 6-fold higher in skin human diploid fibroblasts exposed to UVB in conditions inducing premature senescence when compared to control cells without exposure to UVB. The apparent decrease in HO production from 0 to 72 h after the last exposure to UVB was not due to increased enzymatic activity of catalase or glutathione peroxidase.
Original languageEnglish
Pages (from-to)72-77
Number of pages6
JournalAnnals of the New York academy of sciences
Volume1119
Issue number1
DOIs
Publication statusPublished - 1 Nov 2007

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