Tn951: a new transposon carrying a lactose operon

G Cornelis, D Ghosal, H Saedler

    Research output: Contribution to journalArticlepeer-review


    A new transposon, Tn951, is described, which derives from plasmid pGC1, originally isolated from Yersinia enterocolitica. Tn951 is 16.6 kb long and presumably flanked by small inverted repeats. It carries the lac genes i, z and y. This lac system is homologous to the E. coli lac operon. However, homology is restricted to 5.6 kb. The DNA sequences surrounding the lac operons on Tn951 and E. coli are nonhomologous. This leads to speculations about the origin of the E. coli lac operon itself.
    Original languageEnglish
    Pages (from-to)215-24
    Number of pages10
    JournalMolecular & general genetics : MGG
    Issue number2
    Publication statusPublished - 1978


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