Three 5H-indeno[1,2-c]pyridazin-5-one derivatives, potent type-B monoamine oxidase inhibitors

Raphaël Frédérick, Bernadette Norberg, Fraņcois Durant, Frederic Ooms, Johan Wouters

Research output: Contribution to journalArticlepeer-review

Abstract

The structures of three 5-H-indeno[1,2-c]pyridazin-5-one derivatives, potent type-B monoamine oxidase inhibitors, were investigated. The crystal structures were found to be stabilized by weak C-H⋯O hydrogen bonds. The packing was dominated by π-π stacking interactions between the heterocyclic central moieties of centrosymmetrically related molecules. The π-π stacking network led to a parallel arrangement along the a axis.

Original languageEnglish
JournalActa crystallographica. Section C: Crystal structure communications
Volume60
Issue number9
DOIs
Publication statusPublished - 1 Sept 2004

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