Projects per year
Abstract
One Health is an interdisciplinary collaboration that aims at mitigating risks to human health arising from microorganisms present in non-human animal species, which have the potential to be transmitted and cause disease in humans. Different degrees of scientific collaboration and sectoral integration are needed for different types of zoonotic diseases, depending on the health and associated economic gains that can be expected from a One Health approach. Indeed, mitigating zoonotic risks related to emerging diseases with pandemic potential is different from mitigating risks related to endemic zoonotic diseases like brucellosis. Likewise, management of brucellosis at the wildlife-livestock interface in wildlife conservation areas is in essence different from mitigating transmission of a given Brucella species within its preferential host species, which in turn is different from mitigating the spillover of a given Brucella species to non-preferential host species, humans included. Brucellosis economic models often oversimplify and/or wrongly assess transmission between reservoir hosts and spillover hosts. Moreover, they may not properly value non-market outcomes, such as avoidance of human disease, consumer confidence and conservation biology issues. As a result, uncertainty is such that the economic predictions of these models can be questionable. Therefore, understanding the infection biology of Brucella species is a prerequisite. This paper reviews and highlights important features of the infection biology of Brucella species and the changing epidemiology of brucellosis that need to be integrated into a true One Health perspective of brucellosis.
Original language | English |
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Pages (from-to) | 521-538 |
Number of pages | 18 |
Journal | Revue scientifique et technique (International Office of Epizootics) |
Volume | 33 |
Issue number | 2 |
Publication status | Published - Aug 2014 |
Keywords
- Brucella spp.
- Brucellosis
- Diagnostic
- Epidemiology
- Host specificity
- Immunity
- Infection biology
- One Health
- Resistance
- Zoonosis
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Dive into the research topics of 'The quest for a true One Health perspective of brucellosis'. Together they form a unique fingerprint.Projects
- 2 Finished
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Mécanismes de contrôle du cycle cellulaire de Brucella abortus en cours d'infection
De Bolle, X. (PI)
1/07/13 → 30/06/15
Project: Research
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PAI n°P7/28 - MICRODEV: PAI n°P7/28 - MICRODEV: Role of developmental processes in the virulence of human pathogens : from molecular mechanisms to novel therapeutic targets
LETESSON, J.-J. (CoI), Coenye, T. (PI), Van Dijck, P. (CoI), Van Melderen, L. (CoI), HOLS, P. (CoI) & De Bolle, X. (CoI)
1/10/12 → 30/09/17
Project: Research
Equipment
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Biological Security Laboratory Level 3 (BL3)
De Bolle, X. (Manager)
Technological Platform: Biological Security Laboratory Level 3Facility/equipment: Technological Platform