Synthesis of PEI-Functionalized Magnetic Nanoparticles for Capturing Bacteria

Baoli Chen, Hao Xie, Ao Zhang, Nian Liu, Qichang Li, Junhui Guo, Baolian Su

Research output: Contribution to journalArticlepeer-review

Abstract

Polyethyleneimine (PEI) functionalized Fe 3 O 4 MNPs were synthesized by a modified hypothermal oxidative hydrolysis method. The magnetic nanoparticles showed positively charged surface, strong magnetic responsivity and uniform particle size distribution at 56.1±0.6 nm. Aggregation of these magnetic nanoparticles were observed on the surface of different type of bacteria. Magnetic capturing of bacteria were facilitated by these magnetic nanoparticles. The capturing efficiency could reach 90% after two rounds of interactions of 5 minutes. The mechanism and process of interactions between bacteria and polyethyleneimine functionalized Fe 3 O 4 magnetic nanoparticles were explored and discussed. The present study not only provides insight into interactions between Fe 3 O 4 @PEI MNPs and bacterial cells, but also opens a new avenue for designing and applying Fe 3 O 4 @PEI MNPs as biosensors in microbiology, medicine, and environmental science.

Original languageEnglish
Pages (from-to)236-242
Number of pages7
JournalJournal Wuhan University of Technology, Materials Science Edition
Volume34
Issue number1
DOIs
Publication statusPublished - 1 Feb 2019

Keywords

  • bacterial surface
  • magnetic nanoparticles (MNPs)
  • magnetic separation
  • polyethyleneimine (PEI)

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