2,2,5,5-Tetramethylcyclohexane-1,3-dione is a valuable starting-material precursor of cis-chrysanthemic acid. The (1S)-stereoisomer is a precursor of pyrethrin I, the most active natural insecticide from Chrysanthemum cinerariifolium, whereas the (1R)-stereoisomer is efficiently transformed to deltamethrin, the most active commercially available pyrethroid insecticide. Several intermediates have been identified and used with variable success for that purpose.
Krief, A., Jeanmart, S., Gondal, H. Y., & Kremer, A. (2012). Syntheses of racemic and scalemic cis-chrysanthemic acid from β,γ-unsaturated cyclohexanol. Helvetica chimica acta, 95(11), 2123-2167. https://doi.org/10.1002/hlca.201200393