Structure determination and comparison of BM567, a sulfonylurea, with terbogrel, two compounds with dual action, thromboxane receptor antagonism and thromboxane synthase inhibition

Catherine Michaux; Stéphanie Rolin; Jean-Michel Dogne; François Durant; Bernard Masereel; Jacques Delarge; Johan Wouters

doi:10.1016/S0960-894X(01)00114-7

Structure determination and comparison of BM567, a sulfonylurea, with terbogrel, two compounds with dual action, thromboxane receptor antagonism and thromboxane synthase inhibition

Catherine Michaux, Stéphanie Rolin, Jean-Michel Dogne, François Durant, Bernard Masereel, Jacques Delarge, Johan Wouters

Unit of theoretical and structural physico-chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

BM567, a sulfonylurea compound - whose crystal structure is here discussed - and terbogrel, are both thromboxane receptor antagonists and thromboxane synthase inhibitors. In this paper, their crystallographic and electronic structures are compared and lead to new synthesis prospects among the sulfonylurea series.

Original language	English
Pages (from-to)	1019-1022
Number of pages	4
Journal	Bioorganic & Medicinal Chemistry Letters
Volume	11
Issue number	8
DOIs	https://doi.org/10.1016/S0960-894X(01)00114-7
Publication status	Published - 23 Apr 2001

Access to Document

10.1016/S0960-894X(01)00114-7

Cite this

Michaux, C., Rolin, S., Dogne, J.-M., Durant, F., Masereel, B., Delarge, J., & Wouters, J. (2001). Structure determination and comparison of BM567, a sulfonylurea, with terbogrel, two compounds with dual action, thromboxane receptor antagonism and thromboxane synthase inhibition. Bioorganic & Medicinal Chemistry Letters, 11(8), 1019-1022. https://doi.org/10.1016/S0960-894X(01)00114-7

@article{d7e1ff402bbf48c897b49a92bc61cf4b,

title = "Structure determination and comparison of BM567, a sulfonylurea, with terbogrel, two compounds with dual action, thromboxane receptor antagonism and thromboxane synthase inhibition",

abstract = "BM567, a sulfonylurea compound - whose crystal structure is here discussed - and terbogrel, are both thromboxane receptor antagonists and thromboxane synthase inhibitors. In this paper, their crystallographic and electronic structures are compared and lead to new synthesis prospects among the sulfonylurea series.",

author = "Catherine Michaux and St{\'e}phanie Rolin and Jean-Michel Dogne and Fran{\c c}ois Durant and Bernard Masereel and Jacques Delarge and Johan Wouters",

year = "2001",

month = apr,

day = "23",

doi = "10.1016/S0960-894X(01)00114-7",

language = "English",

volume = "11",

pages = "1019--1022",

journal = "Bioorganic & Medicinal Chemistry Letters",

issn = "0960-894X",

publisher = "Elsevier",

number = "8",

}

Michaux, C, Rolin, S, Dogne, J-M , Durant, F , Masereel, B, Delarge, J & Wouters, J 2001, 'Structure determination and comparison of BM567, a sulfonylurea, with terbogrel, two compounds with dual action, thromboxane receptor antagonism and thromboxane synthase inhibition', Bioorganic & Medicinal Chemistry Letters, vol. 11, no. 8, pp. 1019-1022. https://doi.org/10.1016/S0960-894X(01)00114-7

Structure determination and comparison of BM567, a sulfonylurea, with terbogrel, two compounds with dual action, thromboxane receptor antagonism and thromboxane synthase inhibition. / Michaux, Catherine; Rolin, Stéphanie; Dogne, Jean-Michel et al.
In: Bioorganic & Medicinal Chemistry Letters, Vol. 11, No. 8, 23.04.2001, p. 1019-1022.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Structure determination and comparison of BM567, a sulfonylurea, with terbogrel, two compounds with dual action, thromboxane receptor antagonism and thromboxane synthase inhibition

AU - Michaux, Catherine

AU - Rolin, Stéphanie

AU - Dogne, Jean-Michel

AU - Durant, François

AU - Masereel, Bernard

AU - Delarge, Jacques

AU - Wouters, Johan

PY - 2001/4/23

Y1 - 2001/4/23

N2 - BM567, a sulfonylurea compound - whose crystal structure is here discussed - and terbogrel, are both thromboxane receptor antagonists and thromboxane synthase inhibitors. In this paper, their crystallographic and electronic structures are compared and lead to new synthesis prospects among the sulfonylurea series.

AB - BM567, a sulfonylurea compound - whose crystal structure is here discussed - and terbogrel, are both thromboxane receptor antagonists and thromboxane synthase inhibitors. In this paper, their crystallographic and electronic structures are compared and lead to new synthesis prospects among the sulfonylurea series.

UR - http://www.scopus.com/inward/record.url?scp=0035938408&partnerID=8YFLogxK

U2 - 10.1016/S0960-894X(01)00114-7

DO - 10.1016/S0960-894X(01)00114-7

M3 - Article

C2 - 11327579

AN - SCOPUS:0035938408

SN - 0960-894X

VL - 11

SP - 1019

EP - 1022

JO - Bioorganic & Medicinal Chemistry Letters

JF - Bioorganic & Medicinal Chemistry Letters

IS - 8

ER -

Structure determination and comparison of BM567, a sulfonylurea, with terbogrel, two compounds with dual action, thromboxane receptor antagonism and thromboxane synthase inhibition

Abstract

Access to Document

Other files and links

Fingerprint

Cite this