Structural characterization of oxidized lumiflavin hydrochloride hydrate: Comparison with the hydrogen bonding at the cofactor of flavoproteins

J. Wouters, F. Moureau, Ph Perpète, B. Norberg, G. Evrard, F. Durant

Research output: Contribution to journalArticlepeer-review

Abstract

In order to examine the possibility of hydrogen bonding around the flavin ring, an X-ray diffraction study of the title compound was undertaken. Crystals of lumiflavin hydrochloride hydrate [2(C13H12N4O2) 4 HCl 7 H2O] are triclinic, space group {Mathematical expression}, Z=2, a=11.064(1), b=17.903(1), c=9.891(1)Å, α=111.9(6), β-96.4(8), γ=91.6(7)°. We present the crystal structure of this compound and compare it with other flavin derivatives and with the structure of the active site of some flavoproteins.

Original languageEnglish
Pages (from-to)607-614
Number of pages8
JournalJournal of chemical crystallography
Volume24
Issue number9
DOIs
Publication statusPublished - 1 Sep 1994

Keywords

  • cofactor flavoproteins
  • hydrochloride hydrate
  • hydrogen bonding
  • Oxidized lumiflavin

Fingerprint

Dive into the research topics of 'Structural characterization of oxidized lumiflavin hydrochloride hydrate: Comparison with the hydrogen bonding at the cofactor of flavoproteins'. Together they form a unique fingerprint.

Cite this