Structural approach of the mechanism of inhibition of α-chymotrypsin by coumarins

Johan Wouters, Marjorie Huygens, Lionel Pochet, Bernard Pirotte, François Durant, Bernard Masereel

Research output: Contribution to journalArticlepeer-review

Abstract

A pharmacophore associated to the inhibiton of α-chymotrypsin has been built based on the structural and electronic characterization of a series of coumarin derivatives. © 2002 Elsevier Science Ltd. All rights reserved.

Original languageEnglish
Pages (from-to)1109-1112
Number of pages4
JournalBioorganic and medicinal chemistry letters
Volume12
Issue number7
DOIs
Publication statusPublished - 8 Apr 2002

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