Structural and enzymatic study of tryptophan 2,3-dioxgenase (TDO), a potential target in anticancer immunotherapy.

Laurence Moineaux; Caroline Charlier; Eduard Dolušić; Pierre Larrieu; Luc Pilotte; Didier Colaux; Vincent Stroobant; Moreno Galleni; Bernard Masereel; Benoît Van den Eynde; Johan Wouters; Raphaël Frédérick

Structural and enzymatic study of tryptophan 2,3-dioxgenase (TDO), a potential target in anticancer immunotherapy.

Laurence Moineaux, Caroline Charlier, Eduard Dolušić, Pierre Larrieu, Luc Pilotte, Didier Colaux, Vincent Stroobant, Moreno Galleni, Bernard Masereel, Benoît Van den Eynde, Johan Wouters, Raphaël Frédérick

Research output: Contribution to journal › Literature review › peer-review

Original language	French
Pages (from-to)	189
Journal	Drugs of the future
Volume	35
Issue number	suppl A
Publication status	Published - 2010
Event	EFMC-ISMC 2010 XXIst INTERNATIONAL SYMPOSIUM ON MEDICINAL CHEMISTRY - Bruxelles, Belgium Duration: 5 Sep 2010 → …

3 Finished

tryptophane 2,3-dioxygénase
WOUTERS, J.
1/10/11 → 30/09/13
Project: Research
CANTOL: Design and synthesis of indolamine dioxygenase (IDO) for the treatment of cancer
MASEREEL, B., WOUTERS, J., Dolušić, E., FREDERICK, R., POUYEZ, J., Van den Eynde, B. J., Frère, J., Moser, M., Jean-Marie, B., Combalbert, J. & Stephenne, J.
1/04/08 → 31/03/12
Project: Research
Design, synthesis and study of enzyme modulators implicated in tryptophan metabolism and particularly in the kynurenin pathway
FREDERICK, R.
1/10/07 → 30/09/10
Project: Research

Physical Chemistry and characterization(PC2)
Johan Wouters (Manager) & Carmela Aprile (Manager)
Technological Platform Physical Chemistry and characterization
Facility/equipment: Technological Platform

4 Participation in conference

Heterocycles in Bio-organic Chemistry
Eduard Dolusic (Poster)
27 May 2013
Activity: Participating in or organising an event types › Participation in conference
Annual One-Day Symposium on Medicinal Chemistry of SRC & KVCV (Medchem 2012)
Eduard Dolusic (Contributor)
30 Nov 2012
Activity: Participating in or organising an event types › Participation in conference
BOSS XIII - 13th Belgian Organic Synthesis Symposium Louvain, 15 - 20 juillet 2012
Eduard Dolusic (Poster)
15 Jul 2012
Activity: Participating in or organising an event types › Participation in conference

Conception, synthèse et étude d’inhibiteurs de la tryptophane 2,3-dioxygénase (TDO), une cible prometteuse pour le traitement du cancer
Author: Moineaux, L., 30 Jan 2012
Supervisor: Wouters, J. (Supervisor), Lanners, S. (President), Masereel, B. (Jury), Galleni, M. (External person) (Jury) & Frederick, R. (Jury)
Student thesis: Doc types › Doctor of Sciences

File
Rational design, synthesis, molecular modeling and evaluation of β-carboline and 5H-indeno[1,2-c]pyridazin-5-one derivatives as potential MAO and IDO inhibitors
Author: Reniers, J., 4 Oct 2011
Supervisor: Wouters, J. (Supervisor), Frederick, R. (Jury), Michiels, C. (Jury), Vincent, S. (President) & Kiss, R. (External person) (Jury)
Student thesis: Doc types › Doctor of Sciences

File
Synthèse d'inhibiteurs d'indoleamine-2,3-dioxygenases (IDO et TDO) deux enzymes dont les propriétés immunosuppressives en font des cibles majeures pour le traitement du cancer
Author: Modaffari, S., 2010
Supervisor: Frederick, R. (Supervisor) & Dolusic, E. (Jury)
Student thesis: Master types › Master in Chemistry

Cite this

Moineaux, Laurence ; Charlier, Caroline ; Dolušić, Eduard ; Larrieu, Pierre ; Pilotte, Luc ; Colaux, Didier ; Stroobant, Vincent ; Galleni, Moreno ; Masereel, Bernard ; Van den Eynde, Benoît ; Wouters, Johan ; Frédérick, Raphaël. / Structural and enzymatic study of tryptophan 2,3-dioxgenase (TDO), a potential target in anticancer immunotherapy. In: Drugs of the future. 2010 ; Vol. 35, No. suppl A. pp. 189.

@article{236962cdc8d6433587faf33aedbc4343,

title = "Structural and enzymatic study of tryptophan 2,3-dioxgenase (TDO), a potential target in anticancer immunotherapy.",

author = "Laurence Moineaux and Caroline Charlier and Eduard Dolu{\v s}i{\'c} and Pierre Larrieu and Luc Pilotte and Didier Colaux and Vincent Stroobant and Moreno Galleni and Bernard Masereel and {Van den Eynde}, Beno{\^i}t and Johan Wouters and Rapha{\"e}l Fr{\'e}d{\'e}rick",

year = "2010",

language = "Fran{\c c}ais",

volume = "35",

pages = "189",

journal = "Drugs of the future",

issn = "0377-8282",

publisher = "Prous Science",

number = "suppl A",

note = "EFMC-ISMC 2010 XXIst INTERNATIONAL SYMPOSIUM ON MEDICINAL CHEMISTRY ; Conference date: 05-09-2010",

}

Structural and enzymatic study of tryptophan 2,3-dioxgenase (TDO), a potential target in anticancer immunotherapy. / Moineaux, Laurence; Charlier, Caroline; Dolušić, Eduard; Larrieu, Pierre; Pilotte, Luc; Colaux, Didier; Stroobant, Vincent; Galleni, Moreno; Masereel, Bernard; Van den Eynde, Benoît; Wouters, Johan; Frédérick, Raphaël.

In: Drugs of the future, Vol. 35, No. suppl A, 2010, p. 189.

Research output: Contribution to journal › Literature review › peer-review

TY - JOUR

T1 - Structural and enzymatic study of tryptophan 2,3-dioxgenase (TDO), a potential target in anticancer immunotherapy.

AU - Moineaux, Laurence

AU - Charlier, Caroline

AU - Dolušić, Eduard

AU - Larrieu, Pierre

AU - Pilotte, Luc

AU - Colaux, Didier

AU - Stroobant, Vincent

AU - Galleni, Moreno

AU - Masereel, Bernard

AU - Van den Eynde, Benoît

AU - Wouters, Johan

AU - Frédérick, Raphaël

PY - 2010

Y1 - 2010

M3 - Revue de documentation

VL - 35

SP - 189

JO - Drugs of the future

JF - Drugs of the future

SN - 0377-8282

IS - suppl A

T2 - EFMC-ISMC 2010 XXIst INTERNATIONAL SYMPOSIUM ON MEDICINAL CHEMISTRY

Y2 - 5 September 2010

ER -