Structural and enzymatic study of tryptophan 2,3-dioxgenase (TDO), a potential target in anticancer immunotherapy.

Laurence Moineaux, Caroline Charlier, Eduard Dolušić, Pierre Larrieu, Luc Pilotte, Didier Colaux, Vincent Stroobant, Moreno Galleni, Bernard Masereel, Benoît Van den Eynde, Johan Wouters, Raphaël Frédérick

Research output: Contribution to journalLiterature review

Original languageFrench
Pages (from-to)189
JournalDrugs of the future
Volume35
Issue numbersuppl A
Publication statusPublished - 2010
EventEFMC-ISMC 2010 XXIst INTERNATIONAL SYMPOSIUM ON MEDICINAL CHEMISTRY - Bruxelles, Belgium
Duration: 5 Sep 2010 → …

Projects

tryptophane 2,3-dioxygénase

WOUTERS, J.

1/10/1130/09/13

Project: Research

CANTOL: Design and synthesis of indolamine dioxygenase (IDO) for the treatment of cancer

MASEREEL, B., WOUTERS, J., Dolušić, E., FREDERICK, R., POUYEZ, J., Van den Eynde, B. J., Frère, J., Moser, M., Jean-Marie, B., Combalbert, J. & Stephenne, J.

1/04/0831/03/12

Project: Research

Equipment

  • Activities

    • 4 Participation in conference

    Heterocycles in Bio-organic Chemistry

    Eduard Dolusic (Poster)

    27 May 2013

    Activity: Participating in or organising an event typesParticipation in conference

    Annual One-Day Symposium on Medicinal Chemistry of SRC & KVCV (Medchem 2012)

    Eduard Dolusic (Contributor)

    30 Nov 2012

    Activity: Participating in or organising an event typesParticipation in conference

    BOSS XIII - 13th Belgian Organic Synthesis Symposium Louvain, 15 - 20 juillet 2012

    Eduard Dolusic (Poster)

    15 Jul 2012

    Activity: Participating in or organising an event typesParticipation in conference

    Student Theses

    Conception, synthèse et étude d’inhibiteurs de la tryptophane 2,3-dioxygénase (TDO), une cible prometteuse pour le traitement du cancer

    Author: Moineaux, L., 30 Jan 2012

    Supervisor: Wouters, J. (Supervisor), Lanners, S. (President), Masereel, B. (Jury), Galleni, M. (External person) (Jury) & Frederick, R. (Jury)

    Student thesis: Doc typesDoctor of Sciences

    File

    Rational design, synthesis, molecular modeling and evaluation of β-carboline and 5H-indeno[1,2-c]pyridazin-5-one derivatives as potential MAO and IDO inhibitors

    Author: Reniers, J., 4 Oct 2011

    Supervisor: Wouters, J. (Supervisor), Frederick, R. (Jury), Michiels, C. (Jury), Vincent, S. (President) & Kiss, R. (External person) (Jury)

    Student thesis: Doc typesDoctor of Sciences

    File

    Synthèse d'inhibiteurs d'indoleamine-2,3-dioxygenases (IDO et TDO) deux enzymes dont les propriétés immunosuppressives en font des cibles majeures pour le traitement du cancer

    Author: Modaffari, S., 2010

    Supervisor: Frederick, R. (Supervisor) & Dolusic, E. (Jury)

    Student thesis: Master typesMaster in Chemistry

    Cite this

    Moineaux, L., Charlier, C., Dolušić, E., Larrieu, P., Pilotte, L., Colaux, D., Stroobant, V., Galleni, M., Masereel, B., Van den Eynde, B., Wouters, J., & Frédérick, R. (2010). Structural and enzymatic study of tryptophan 2,3-dioxgenase (TDO), a potential target in anticancer immunotherapy. Drugs of the future, 35(suppl A), 189.