Stress-induced premature senescence: From biomarkers to likeliness of in vivo occurrence

Olivier Toussaint, José Remacle, Jean François Dierick, Thierry Pascal, Christophe Frippiat, Véronique Royer, Joao Pedro Magalhacs, Stéphanie Zdanov, Florence Chainiaux

Research output: Contribution to journalArticle

Abstract

The similarities between the biomarkers of stress-induced premature senescence and replicative senescence are reviewed. The possibility of existence of 'molecular scars', i.e. long-term changes observed after subcytotoxic stress and not observed in replicative senescence, is considered. Lastly, the likeliness of existence of stress-induced premature senescence in vivo is discussed. The possible effects on normal and pathological tissue ageing are predicted.

Original languageEnglish
Pages (from-to)13-17
Number of pages5
JournalBiogerontology
Volume3
Issue number1-2
DOIs
Publication statusPublished - 17 Apr 2002

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Cell Aging
Biomarkers
Cicatrix

Keywords

  • Ageing
  • Fibroblast
  • Senescence
  • Stress

Cite this

Toussaint, Olivier ; Remacle, José ; Dierick, Jean François ; Pascal, Thierry ; Frippiat, Christophe ; Royer, Véronique ; Magalhacs, Joao Pedro ; Zdanov, Stéphanie ; Chainiaux, Florence. / Stress-induced premature senescence : From biomarkers to likeliness of in vivo occurrence. In: Biogerontology. 2002 ; Vol. 3, No. 1-2. pp. 13-17.
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Stress-induced premature senescence : From biomarkers to likeliness of in vivo occurrence. / Toussaint, Olivier; Remacle, José; Dierick, Jean François; Pascal, Thierry; Frippiat, Christophe; Royer, Véronique; Magalhacs, Joao Pedro; Zdanov, Stéphanie; Chainiaux, Florence.

In: Biogerontology, Vol. 3, No. 1-2, 17.04.2002, p. 13-17.

Research output: Contribution to journalArticle

TY - JOUR

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AU - Remacle, José

AU - Dierick, Jean François

AU - Pascal, Thierry

AU - Frippiat, Christophe

AU - Royer, Véronique

AU - Magalhacs, Joao Pedro

AU - Zdanov, Stéphanie

AU - Chainiaux, Florence

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