Abstract
This report discloses the first successful cyclization of a squalene analogue bearing a Δ Z instead of E CC bond which leads to a lanosterol analogue possessing the unnatural 20S stereochemistry. The hypotheses of sterol biosynthesis are discussed in the light of these findings.
Original language | English |
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Pages (from-to) | 3103-3106 |
Number of pages | 4 |
Journal | Tetrahedron Letters |
Volume | 20 |
Issue number | 33 |
Publication status | Published - 1 Jan 1979 |