Stable aqueous dispersion of pegylated nanoparticles by polyelectrolyte complex formation

Dilyana Paneva; Laetitia Mespouille; François Bougard; Nevena Manolova; Philippe Degée; Iliya Rashkov; Philippe Dubois

doi:10.1002/marc.200700079

Stable aqueous dispersion of pegylated nanoparticles by polyelectrolyte complex formation

Dilyana Paneva, Laetitia Mespouille, François Bougard, Nevena Manolova, Philippe Degée, Iliya Rashkov, Philippe Dubois

Research output: Contribution to journal › Article › peer-review

Abstract

Stable aqueous dispersions of nanoparticles were prepared by polyelectrolyte complex formation between well-defined poly(ethylene glycol)-block-poly(2-acrylamido-2-methyl-l-propane sodium sulfonate) and poly(ethylene glycol)-block-poly[2-(dimethylamino)ethyl methacrylate] diblock copolymers. Controlled synthesis of the copolymers was achieved by water-based atom transfer radical polymerization (ATRP). The nanoparticles were characterized by a quite narrow and monomodal size distribution as evidenced by dynamic light scattering (DLS) and confirmed by atomic force microscopy (AFM) after solution casting and freeze-drying.

Original language	English
Pages (from-to)	1361-1365
Number of pages	5
Journal	Macromolecular Rapid Communications
Volume	28
Issue number	12
DOIs	https://doi.org/10.1002/marc.200700079
Publication status	Published - 14 Jun 2007
Externally published	Yes

Keywords

Atom transfer radical polymerization (ATRP)
Diblock copolymers
Nanoparticles
Polyelectrolyte complexes (PECs)

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10.1002/marc.200700079

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abstract = "Stable aqueous dispersions of nanoparticles were prepared by polyelectrolyte complex formation between well-defined poly(ethylene glycol)-block-poly(2-acrylamido-2-methyl-l-propane sodium sulfonate) and poly(ethylene glycol)-block-poly[2-(dimethylamino)ethyl methacrylate] diblock copolymers. Controlled synthesis of the copolymers was achieved by water-based atom transfer radical polymerization (ATRP). The nanoparticles were characterized by a quite narrow and monomodal size distribution as evidenced by dynamic light scattering (DLS) and confirmed by atomic force microscopy (AFM) after solution casting and freeze-drying.",

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T1 - Stable aqueous dispersion of pegylated nanoparticles by polyelectrolyte complex formation

AU - Paneva, Dilyana

AU - Mespouille, Laetitia

AU - Bougard, François

AU - Manolova, Nevena

AU - Degée, Philippe

AU - Rashkov, Iliya

AU - Dubois, Philippe

PY - 2007/6/14

Y1 - 2007/6/14

N2 - Stable aqueous dispersions of nanoparticles were prepared by polyelectrolyte complex formation between well-defined poly(ethylene glycol)-block-poly(2-acrylamido-2-methyl-l-propane sodium sulfonate) and poly(ethylene glycol)-block-poly[2-(dimethylamino)ethyl methacrylate] diblock copolymers. Controlled synthesis of the copolymers was achieved by water-based atom transfer radical polymerization (ATRP). The nanoparticles were characterized by a quite narrow and monomodal size distribution as evidenced by dynamic light scattering (DLS) and confirmed by atomic force microscopy (AFM) after solution casting and freeze-drying.

AB - Stable aqueous dispersions of nanoparticles were prepared by polyelectrolyte complex formation between well-defined poly(ethylene glycol)-block-poly(2-acrylamido-2-methyl-l-propane sodium sulfonate) and poly(ethylene glycol)-block-poly[2-(dimethylamino)ethyl methacrylate] diblock copolymers. Controlled synthesis of the copolymers was achieved by water-based atom transfer radical polymerization (ATRP). The nanoparticles were characterized by a quite narrow and monomodal size distribution as evidenced by dynamic light scattering (DLS) and confirmed by atomic force microscopy (AFM) after solution casting and freeze-drying.

KW - Atom transfer radical polymerization (ATRP)

KW - Diblock copolymers

KW - Nanoparticles

KW - Polyelectrolyte complexes (PECs)

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Stable aqueous dispersion of pegylated nanoparticles by polyelectrolyte complex formation

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Keywords

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