Abstract
SeqWord Gene Island Sniffer, a new program for the identification of mobile genetic elements in sequences of bacterial chromosomes is presented. This program is based on the analysis of oligonucleotide usage variations in DNA sequences. 3,518 mobile genetic elements were identified in 637 bacterial genomes and further analyzed by sequence similarity and the functionality of encoded proteins. The results of this study are stored in an open database (http://anjie.bi.up.ac.za/geidb/geidbhome. php). The developed computer program and the database provide the information valuable for further investigation of the distribution of mobile genetic elements and virulence factors among bacteria. The program is available for download at www.bi.up.ac.za/SeqWord/sniffer/index.html.
| Original language | English |
|---|---|
| Pages (from-to) | 410-415 |
| Number of pages | 6 |
| Journal | World Academy of Science, Engineering and Technology |
| Volume | 58 |
| Publication status | Published - Oct 2009 |
| Externally published | Yes |
Keywords
- Bacterial genomes
- Mobile genetic elements
- Virulence