Regioselective end-functionalization of polylactide oligomers with D-glucose and D-galactose

Katty Bernard, Philippe Degée, Philippe Dubois

Research output: Contribution to journalArticlepeer-review

Abstract

D-glucose and D-galactose end-functionalized polylactide oligomers were synthesized by controlled ring-opening polymerization of lactide using aluminium triisopropoxide, triethyl-aluminium or stannous octoate as promoter. Accordingly, two selectively protected monosaccharides were studied as co-initiators, either 1,2;5,6-di-O-isopropylidene-α-D-glucofuranose (1) and 1,2;3,4-di-O-isopropylidene-α-D-galactopyranose (2). In contrast to what is known in polymerization of ε-caprolactone, both protected monosaccharides proved to be efficient co-initiators and yielded end-functionalized polylactide chains with controlled regioselectivity (C-3 or C-6 linkage), predictable molecular weights and narrow molecular weight distributions.

Original languageEnglish
Pages (from-to)406-411
Number of pages6
JournalPolymer international
Volume52
Issue number3
DOIs
Publication statusPublished - 1 Mar 2003
Externally publishedYes

Keywords

  • Functionalization
  • Polylactide
  • Ring-opening polymerization
  • Saccharide

Fingerprint

Dive into the research topics of 'Regioselective end-functionalization of polylactide oligomers with D-glucose and D-galactose'. Together they form a unique fingerprint.

Cite this