Abstract
Purification of recombinant amyloidogenic proteins can sometimes prove challenging due in part to their aggregation-prone character, which prevent the use of acidic buffers or denaturant agents. Here, we demonstrate how we are able to use Bio-Rad's NuviaQ Resin to successfully purify one such protein, transthyretin, under neutral buffer conditions.
Original language | English |
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Journal | Bio-Rad Bulletin |
Volume | 6711 |
Publication status | Published - 2015 |
Externally published | Yes |