Purification of Amyloidogenic Transthyretin Protein Using NuviaQ Anion Exchange Resin

Sébastien Penninckx, Vincent Raussens (Supervisor), Stéphanie Deroo (Supervisor)

Research output: Contribution to journalArticle


Purification of recombinant amyloidogenic proteins can sometimes prove challenging due in part to their aggregation-prone character, which prevent the use of acidic buffers or denaturant agents. Here, we demonstrate how we are able to use Bio-Rad's NuviaQ Resin to successfully purify one such protein, transthyretin, under neutral buffer conditions.
Original languageEnglish
JournalBio-Rad Bulletin
Publication statusPublished - 2015
Externally publishedYes

Cite this