Prothrombotic disturbances of hemostasis of patients with severe COVID-19: A prospective longitudinal observational study

Michaël Hardy; Isabelle Michaux; Sarah Lessire; Jonathan Douxfils; Jean-Michel Dogné; Marion Bareille; Geoffrey Horlait; Pierre Bulpa; Céline Chapelle; Silvy Laporte; Sophie Testa; Hugues Jacqmin; Thomas Lecompte; Alain Dive; François Mullier

doi:10.1016/j.thromres.2020.10.025

Prothrombotic disturbances of hemostasis of patients with severe COVID-19: A prospective longitudinal observational study

Michaël Hardy, Isabelle Michaux, Sarah Lessire, Jonathan Douxfils, Jean-Michel Dogné, Marion Bareille, Geoffrey Horlait, Pierre Bulpa, Céline Chapelle, Silvy Laporte, Sophie Testa, Hugues Jacqmin, Thomas Lecompte, Alain Dive, François Mullier

University of Namur

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Original language	English
Pages (from-to)	20-23
Number of pages	4
Journal	Thrombosis Research
Volume	197
Early online date	2020
DOIs	https://doi.org/10.1016/j.thromres.2020.10.025
Publication status	Published - Jan 2021

Keywords

COVID19
Fibrinolysis
intensive care
PAI-1
D-dimers
fibrinogen
factor VIII
Intensive care
Factor VIII
Fibrinogen
Thrombin generation

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.thromres.2020.10.025

2020_HardyMEtal_articleProof, 24.7 MB

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Hardy, M., Michaux, I., Lessire, S., Douxfils, J., Dogné, J-M., Bareille, M., Horlait, G., Bulpa, P., Chapelle, C., Laporte, S., Testa, S., Jacqmin, H., Lecompte, T., Dive, A., & Mullier, F. (2021). Prothrombotic disturbances of hemostasis of patients with severe COVID-19: A prospective longitudinal observational study. Thrombosis Research, 197, 20-23. https://doi.org/10.1016/j.thromres.2020.10.025

@article{2e537a54b55840dc94fdf0511e30cbdf,

title = "Prothrombotic disturbances of hemostasis of patients with severe COVID-19: A prospective longitudinal observational study",

keywords = "COVID19, Fibrinolysis, intensive care, PAI-1, D-dimers, fibrinogen, factor VIII, Intensive care, Factor VIII, Fibrinogen, Thrombin generation",

author = "Micha{\"e}l Hardy and Isabelle Michaux and Sarah Lessire and Jonathan Douxfils and Jean-Michel Dogn{\'e} and Marion Bareille and Geoffrey Horlait and Pierre Bulpa and C{\'e}line Chapelle and Silvy Laporte and Sophie Testa and Hugues Jacqmin and Thomas Lecompte and Alain Dive and Fran{\c c}ois Mullier",

note = "Funding Information: This study was supported by the Fonds National de la Recherche Scientifique (Belgium) : {\textquoteleft}Anticoagulation fibrinolysis COVID19{\textquoteright} (reference: 40002796 ). The instrument and reagents for Global Fibrinolytic Capacity assay (Lysis Timer) were provided by Hyphen Biomed.",

year = "2021",

month = jan,

doi = "10.1016/j.thromres.2020.10.025",

language = "English",

volume = "197",

pages = "20--23",

journal = "Thrombosis Research",

issn = "0049-3848",

publisher = "Elsevier",

}

Hardy, M, Michaux, I, Lessire, S, Douxfils, J , Dogné, J-M, Bareille, M, Horlait, G, Bulpa, P, Chapelle, C, Laporte, S, Testa, S, Jacqmin, H, Lecompte, T, Dive, A & Mullier, F 2021, 'Prothrombotic disturbances of hemostasis of patients with severe COVID-19: A prospective longitudinal observational study', Thrombosis Research, vol. 197, pp. 20-23. https://doi.org/10.1016/j.thromres.2020.10.025

TY - JOUR

T1 - Prothrombotic disturbances of hemostasis of patients with severe COVID-19

T2 - A prospective longitudinal observational study

AU - Hardy, Michaël

AU - Michaux, Isabelle

AU - Lessire, Sarah

AU - Douxfils, Jonathan

AU - Dogné, Jean-Michel

AU - Bareille, Marion

AU - Horlait, Geoffrey

AU - Bulpa, Pierre

AU - Chapelle, Céline

AU - Laporte, Silvy

AU - Testa, Sophie

AU - Jacqmin, Hugues

AU - Lecompte, Thomas

AU - Dive, Alain

AU - Mullier, François

N1 - Funding Information: This study was supported by the Fonds National de la Recherche Scientifique (Belgium) : ‘Anticoagulation fibrinolysis COVID19’ (reference: 40002796 ). The instrument and reagents for Global Fibrinolytic Capacity assay (Lysis Timer) were provided by Hyphen Biomed.

PY - 2021/1

Y1 - 2021/1

KW - COVID19

KW - Fibrinolysis

KW - intensive care

KW - PAI-1

KW - D-dimers

KW - fibrinogen

KW - factor VIII

KW - Intensive care

KW - Factor VIII

KW - Fibrinogen

KW - Thrombin generation

UR - http://www.scopus.com/inward/record.url?scp=85095458861&partnerID=8YFLogxK

U2 - 10.1016/j.thromres.2020.10.025

DO - 10.1016/j.thromres.2020.10.025

M3 - Article

C2 - 33161283

VL - 197

SP - 20

EP - 23

JO - Thrombosis Research

JF - Thrombosis Research

SN - 0049-3848

ER -

Prothrombotic disturbances of hemostasis of patients with severe COVID-19: A prospective longitudinal observational study

Keywords

UN SDGs

Access to Document

Other files and links

The COVILAB project : Clinical laboratory investigations related to COVID-19

Cite this

Prothrombotic disturbances of hemostasis of patients with severe COVID-19: A prospective longitudinal observational study

Keywords

UN SDGs

Access to Document

Other files and links

Projects

The COVILAB project : Clinical laboratory investigations related to COVID-19

Cite this