Abstract
Soluble cytokine receptors (sCRs) modulate the in vivo activity of cytokines. Deficient sCR production could participate in the pathogenesis and course of Crohn's disease (CD). The aim of the study was to examine the profile of sCRs in CD patients and their modulation by infliximab and corticosteroids.
Original language | English |
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Pages (from-to) | 488-95 |
Number of pages | 8 |
Journal | Gut |
Volume | 54 |
Issue number | 4 |
DOIs | |
Publication status | Published - Apr 2005 |
Keywords
- Adrenal Cortex Hormones
- Adult
- Antibodies, Monoclonal
- Antigens, CD
- C-Reactive Protein
- Colitis, Ulcerative
- Crohn Disease
- Cytokine Receptor gp130
- Female
- Gastrointestinal Agents
- Humans
- Immunity, Mucosal
- Interleukin-6
- Intestinal Mucosa
- Ligands
- Male
- Membrane Glycoproteins
- Middle Aged
- Prospective Studies
- Receptors, Cytokine
- Remission Induction
- Solubility
- Tissue Culture Techniques
- Tumor Necrosis Factor-alpha