Profile of soluble cytokine receptors in Crohn's disease

T Gustot, A Lemmers, E Louis, C Nicaise, E Quertinmont, J Belaiche, S Roland, A Van Gossum, J Devière, D Franchimont

Research output: Contribution to journalArticlepeer-review

Abstract

Soluble cytokine receptors (sCRs) modulate the in vivo activity of cytokines. Deficient sCR production could participate in the pathogenesis and course of Crohn's disease (CD). The aim of the study was to examine the profile of sCRs in CD patients and their modulation by infliximab and corticosteroids.
Original languageEnglish
Pages (from-to)488-95
Number of pages8
JournalGut
Volume54
Issue number4
DOIs
Publication statusPublished - Apr 2005

Keywords

  • Adrenal Cortex Hormones
  • Adult
  • Antibodies, Monoclonal
  • Antigens, CD
  • C-Reactive Protein
  • Colitis, Ulcerative
  • Crohn Disease
  • Cytokine Receptor gp130
  • Female
  • Gastrointestinal Agents
  • Humans
  • Immunity, Mucosal
  • Interleukin-6
  • Intestinal Mucosa
  • Ligands
  • Male
  • Membrane Glycoproteins
  • Middle Aged
  • Prospective Studies
  • Receptors, Cytokine
  • Remission Induction
  • Solubility
  • Tissue Culture Techniques
  • Tumor Necrosis Factor-alpha

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