Platelet ADP receptors and their antagonists

Patricia Benoit, Jean-Michel Dogné

Research output: Contribution to journalArticlepeer-review

Abstract

ADP plays a crucial role in haemostasis and thrombosis and its receptors are potential target for antithrombotic drugs. The knowledge of the ADP-receptors has been amplified by recent discoveries. This review highlights the ADP-receptors models and their antagonists described in the recent literature, mainly the thienopyridine derivatives.
Original languageEnglish
Pages (from-to)145-8
Number of pages4
JournalMini-reviews in medicinal chemistry
Volume3
Issue number2
Publication statusPublished - Mar 2003

Keywords

  • Animals
  • Blood Platelets
  • Fibrinolytic Agents
  • Humans
  • Platelet Activation
  • Platelet Aggregation Inhibitors
  • Purinergic P2 Receptor Antagonists
  • Pyridines
  • Receptors, Purinergic P2
  • Structure-Activity Relationship

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