One-pot synthesis of well-defined amphiphilic and adaptative block copolymers via versatile combination of "click" chemistry and ATRP

Laetitia Mespouille, Magali Vachaudez, Fabian Suriano, Pascal Gerbaux, Olivier Coulembier, Philippe Degée, Robert Flammang, Philippe Dubois

Research output: Contribution to journalArticle

Abstract

Well-defined amphiphilic PCL-b-PDMAEMA block copolymers were successfully synthesized by a combination of ATRP and "click" chemistry following either a commutative two-step procedure or a straightforward one-pot process using CuBr · 3Bpy as the sole catalyst. Compared to the traditional coupling method, combining ATRP and click chemistry even in a "one-pot" process allows the preparation of PCL-b-PDMAEMA diblock copolymers characterized by a narrow molecular weight distribution and quantitative conversion of azides and alkynes into triazole functions. Moreover, the amphiphilic character of these copolymers was demonstrated by surface tension measurements and critical micellization concentration was calculated.

Original languageEnglish
Pages (from-to)2151-2158
Number of pages8
JournalMacromolecular Rapid Communications
Volume28
Issue number22
DOIs
Publication statusPublished - 16 Nov 2007
Externally publishedYes

Fingerprint

Atom transfer radical polymerization
Block copolymers
Micellization
Triazoles
Alkynes
Azides
Molecular weight distribution
Surface tension
Copolymers
Catalysts
poly(2-(dimethylamino)ethyl methacrylate)

Keywords

  • Amphiphilic diblock copolymer
  • Atom transfer radical polymerization (ATRP)
  • Huisgen 1,3-dipolar cycloaddition
  • Poly-(ε-caprolactone) (PCL)
  • PolyN,N-dimethylamino-2-ethyl methacrylate (PDMAEMA)
  • Synthesis

Cite this

Mespouille, Laetitia ; Vachaudez, Magali ; Suriano, Fabian ; Gerbaux, Pascal ; Coulembier, Olivier ; Degée, Philippe ; Flammang, Robert ; Dubois, Philippe. / One-pot synthesis of well-defined amphiphilic and adaptative block copolymers via versatile combination of "click" chemistry and ATRP. In: Macromolecular Rapid Communications. 2007 ; Vol. 28, No. 22. pp. 2151-2158.
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One-pot synthesis of well-defined amphiphilic and adaptative block copolymers via versatile combination of "click" chemistry and ATRP. / Mespouille, Laetitia; Vachaudez, Magali; Suriano, Fabian; Gerbaux, Pascal; Coulembier, Olivier; Degée, Philippe; Flammang, Robert; Dubois, Philippe.

In: Macromolecular Rapid Communications, Vol. 28, No. 22, 16.11.2007, p. 2151-2158.

Research output: Contribution to journalArticle

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AU - Mespouille, Laetitia

AU - Vachaudez, Magali

AU - Suriano, Fabian

AU - Gerbaux, Pascal

AU - Coulembier, Olivier

AU - Degée, Philippe

AU - Flammang, Robert

AU - Dubois, Philippe

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