New chips for molecular biology and diagnostics

Nathalie Zammatteo, Sandrine Hamels, Françoise De Longueville, Isabelle Alexandre, Jean-luc Gala, Francis Brasseur, José Remacle

Research output: Contribution in Book/Catalog/Report/Conference proceedingChapter

Abstract

The DNA chips are arrays of DNA probes immobilized on solid support for silmutaneous indentification of many target DNA sequences. DNA chips applied to diagnosis aims to detect genomic DNA or RNA after PCR amplification. This review provides on overview of DNA chip technology, focusing on diagnostic applications. A comparison between high density and low density microarrays is given showing that low density chips are more suitable for routine applications due to their simplicity, good reproducibility, easy data management and low cost.
Original languageEnglish
Title of host publicationBiotechnology Annual Report
EditorsEl Gewely
Pages85-101
Number of pages17
Volume8
Publication statusPublished - 2002

Fingerprint

Molecular biology
DNA
DNA sequences
DNA Probes
Microarrays
Information management
Amplification
RNA
Costs

Keywords

  • DNA microarray
  • diagnosis

Cite this

Zammatteo, N., Hamels, S., De Longueville, F., Alexandre, I., Gala, J., Brasseur, F., & Remacle, J. (2002). New chips for molecular biology and diagnostics. In E. Gewely (Ed.), Biotechnology Annual Report (Vol. 8, pp. 85-101)
Zammatteo, Nathalie ; Hamels, Sandrine ; De Longueville, Françoise ; Alexandre, Isabelle ; Gala, Jean-luc ; Brasseur, Francis ; Remacle, José. / New chips for molecular biology and diagnostics. Biotechnology Annual Report. editor / El Gewely. Vol. 8 2002. pp. 85-101
@inbook{6d1b35fa994b4d65862b07c6988b8e84,
title = "New chips for molecular biology and diagnostics",
abstract = "The DNA chips are arrays of DNA probes immobilized on solid support for silmutaneous indentification of many target DNA sequences. DNA chips applied to diagnosis aims to detect genomic DNA or RNA after PCR amplification. This review provides on overview of DNA chip technology, focusing on diagnostic applications. A comparison between high density and low density microarrays is given showing that low density chips are more suitable for routine applications due to their simplicity, good reproducibility, easy data management and low cost.",
keywords = "DNA microarray, diagnosis",
author = "Nathalie Zammatteo and Sandrine Hamels and {De Longueville}, Fran{\cc}oise and Isabelle Alexandre and Jean-luc Gala and Francis Brasseur and Jos{\'e} Remacle",
note = "Publication editors : El Gewely, M.R.",
year = "2002",
language = "English",
volume = "8",
pages = "85--101",
editor = "El Gewely",
booktitle = "Biotechnology Annual Report",

}

Zammatteo, N, Hamels, S, De Longueville, F, Alexandre, I, Gala, J, Brasseur, F & Remacle, J 2002, New chips for molecular biology and diagnostics. in E Gewely (ed.), Biotechnology Annual Report. vol. 8, pp. 85-101.

New chips for molecular biology and diagnostics. / Zammatteo, Nathalie; Hamels, Sandrine; De Longueville, Françoise; Alexandre, Isabelle; Gala, Jean-luc; Brasseur, Francis; Remacle, José.

Biotechnology Annual Report. ed. / El Gewely. Vol. 8 2002. p. 85-101.

Research output: Contribution in Book/Catalog/Report/Conference proceedingChapter

TY - CHAP

T1 - New chips for molecular biology and diagnostics

AU - Zammatteo, Nathalie

AU - Hamels, Sandrine

AU - De Longueville, Françoise

AU - Alexandre, Isabelle

AU - Gala, Jean-luc

AU - Brasseur, Francis

AU - Remacle, José

N1 - Publication editors : El Gewely, M.R.

PY - 2002

Y1 - 2002

N2 - The DNA chips are arrays of DNA probes immobilized on solid support for silmutaneous indentification of many target DNA sequences. DNA chips applied to diagnosis aims to detect genomic DNA or RNA after PCR amplification. This review provides on overview of DNA chip technology, focusing on diagnostic applications. A comparison between high density and low density microarrays is given showing that low density chips are more suitable for routine applications due to their simplicity, good reproducibility, easy data management and low cost.

AB - The DNA chips are arrays of DNA probes immobilized on solid support for silmutaneous indentification of many target DNA sequences. DNA chips applied to diagnosis aims to detect genomic DNA or RNA after PCR amplification. This review provides on overview of DNA chip technology, focusing on diagnostic applications. A comparison between high density and low density microarrays is given showing that low density chips are more suitable for routine applications due to their simplicity, good reproducibility, easy data management and low cost.

KW - DNA microarray

KW - diagnosis

M3 - Chapter

VL - 8

SP - 85

EP - 101

BT - Biotechnology Annual Report

A2 - Gewely, El

ER -

Zammatteo N, Hamels S, De Longueville F, Alexandre I, Gala J, Brasseur F et al. New chips for molecular biology and diagnostics. In Gewely E, editor, Biotechnology Annual Report. Vol. 8. 2002. p. 85-101