New chips for molecular biology and diagnostics

Nathalie Zammatteo, Sandrine Hamels, Françoise De Longueville, Isabelle Alexandre, Jean-luc Gala, Francis Brasseur, José Remacle

Research output: Contribution in Book/Catalog/Report/Conference proceedingChapter

Abstract

The DNA chips are arrays of DNA probes immobilized on solid support for silmutaneous indentification of many target DNA sequences. DNA chips applied to diagnosis aims to detect genomic DNA or RNA after PCR amplification. This review provides on overview of DNA chip technology, focusing on diagnostic applications. A comparison between high density and low density microarrays is given showing that low density chips are more suitable for routine applications due to their simplicity, good reproducibility, easy data management and low cost.
Original languageEnglish
Title of host publicationBiotechnology Annual Report
EditorsEl Gewely
Pages85-101
Number of pages17
Volume8
Publication statusPublished - 2002

Keywords

  • DNA microarray
  • diagnosis

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