Neural correlates of performance variability during motor sequence acquisition

Geneviève Albouy, Virginie Sterpenich, Gilles Vandewalle, Annabelle Darsaud, Steffen Gais, Géraldine Rauchs, Martin Desseilles, Mélanie Boly, Thanh Dang-Vu, Evelyne Balteau, Christian Degueldre, Christophe Phillips, André Luxen, Pierre Maquet

Research output: Contribution to journalArticle

Abstract

During the initial training of a motor sequence, performance becomes progressively faster but also increasingly reproducible and consistent. However, performance temporarily becomes more variable at mid-training, reflecting a change in the motor representation and the eventual selection of the optimal performance mode (Adi-Japha et al., 2008). At the cerebral level, whereas performance speed is known to be related to the activity in cerebello-cortical and striato-cortical networks, the neural correlates of performance variability remain unknown. We characterized the latter using functional magnetic resonance imaging (fMRI) during the initial training to the Finger Tapping Task (FTT), during which participants produced a 5-element finger sequence on a keyboard with their left non-dominant hand. Our results show that responses in the precuneus decrease whereas responses in the caudate nucleus increase as performance becomes more consistent. In addition, a variable performance is associated with enhanced interaction between the hippocampus and fronto-parietal areas and between the striatum and frontal areas. Our results suggest that these dynamic large-scale interactions represent a cornerstone in the implementation of consistent motor behavior in humans.
Original languageEnglish
Pages (from-to)324-31
Number of pages8
JournalNeuroImage
Volume60
Issue number1
DOIs
Publication statusPublished - Mar 2012

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Fingers
Parietal Lobe
Caudate Nucleus
Hippocampus
Hand
Magnetic Resonance Imaging

Keywords

  • Brain
  • Female
  • Humans
  • Learning
  • Magnetic Resonance Imaging
  • Male
  • Task Performance and Analysis
  • Young Adult

Cite this

Albouy, G., Sterpenich, V., Vandewalle, G., Darsaud, A., Gais, S., Rauchs, G., ... Maquet, P. (2012). Neural correlates of performance variability during motor sequence acquisition. NeuroImage, 60(1), 324-31. https://doi.org/10.1016/j.neuroimage.2011.12.049
Albouy, Geneviève ; Sterpenich, Virginie ; Vandewalle, Gilles ; Darsaud, Annabelle ; Gais, Steffen ; Rauchs, Géraldine ; Desseilles, Martin ; Boly, Mélanie ; Dang-Vu, Thanh ; Balteau, Evelyne ; Degueldre, Christian ; Phillips, Christophe ; Luxen, André ; Maquet, Pierre. / Neural correlates of performance variability during motor sequence acquisition. In: NeuroImage. 2012 ; Vol. 60, No. 1. pp. 324-31.
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Albouy, G, Sterpenich, V, Vandewalle, G, Darsaud, A, Gais, S, Rauchs, G, Desseilles, M, Boly, M, Dang-Vu, T, Balteau, E, Degueldre, C, Phillips, C, Luxen, A & Maquet, P 2012, 'Neural correlates of performance variability during motor sequence acquisition', NeuroImage, vol. 60, no. 1, pp. 324-31. https://doi.org/10.1016/j.neuroimage.2011.12.049

Neural correlates of performance variability during motor sequence acquisition. / Albouy, Geneviève; Sterpenich, Virginie; Vandewalle, Gilles; Darsaud, Annabelle; Gais, Steffen; Rauchs, Géraldine; Desseilles, Martin; Boly, Mélanie; Dang-Vu, Thanh; Balteau, Evelyne; Degueldre, Christian; Phillips, Christophe; Luxen, André; Maquet, Pierre.

In: NeuroImage, Vol. 60, No. 1, 03.2012, p. 324-31.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Neural correlates of performance variability during motor sequence acquisition

AU - Albouy, Geneviève

AU - Sterpenich, Virginie

AU - Vandewalle, Gilles

AU - Darsaud, Annabelle

AU - Gais, Steffen

AU - Rauchs, Géraldine

AU - Desseilles, Martin

AU - Boly, Mélanie

AU - Dang-Vu, Thanh

AU - Balteau, Evelyne

AU - Degueldre, Christian

AU - Phillips, Christophe

AU - Luxen, André

AU - Maquet, Pierre

N1 - Copyright © 2012 Elsevier Inc. All rights reserved.

PY - 2012/3

Y1 - 2012/3

N2 - During the initial training of a motor sequence, performance becomes progressively faster but also increasingly reproducible and consistent. However, performance temporarily becomes more variable at mid-training, reflecting a change in the motor representation and the eventual selection of the optimal performance mode (Adi-Japha et al., 2008). At the cerebral level, whereas performance speed is known to be related to the activity in cerebello-cortical and striato-cortical networks, the neural correlates of performance variability remain unknown. We characterized the latter using functional magnetic resonance imaging (fMRI) during the initial training to the Finger Tapping Task (FTT), during which participants produced a 5-element finger sequence on a keyboard with their left non-dominant hand. Our results show that responses in the precuneus decrease whereas responses in the caudate nucleus increase as performance becomes more consistent. In addition, a variable performance is associated with enhanced interaction between the hippocampus and fronto-parietal areas and between the striatum and frontal areas. Our results suggest that these dynamic large-scale interactions represent a cornerstone in the implementation of consistent motor behavior in humans.

AB - During the initial training of a motor sequence, performance becomes progressively faster but also increasingly reproducible and consistent. However, performance temporarily becomes more variable at mid-training, reflecting a change in the motor representation and the eventual selection of the optimal performance mode (Adi-Japha et al., 2008). At the cerebral level, whereas performance speed is known to be related to the activity in cerebello-cortical and striato-cortical networks, the neural correlates of performance variability remain unknown. We characterized the latter using functional magnetic resonance imaging (fMRI) during the initial training to the Finger Tapping Task (FTT), during which participants produced a 5-element finger sequence on a keyboard with their left non-dominant hand. Our results show that responses in the precuneus decrease whereas responses in the caudate nucleus increase as performance becomes more consistent. In addition, a variable performance is associated with enhanced interaction between the hippocampus and fronto-parietal areas and between the striatum and frontal areas. Our results suggest that these dynamic large-scale interactions represent a cornerstone in the implementation of consistent motor behavior in humans.

KW - Brain

KW - Female

KW - Humans

KW - Learning

KW - Magnetic Resonance Imaging

KW - Male

KW - Task Performance and Analysis

KW - Young Adult

U2 - 10.1016/j.neuroimage.2011.12.049

DO - 10.1016/j.neuroimage.2011.12.049

M3 - Article

C2 - 22227134

VL - 60

SP - 324

EP - 331

JO - NeuroImage

JF - NeuroImage

SN - 1053-8119

IS - 1

ER -

Albouy G, Sterpenich V, Vandewalle G, Darsaud A, Gais S, Rauchs G et al. Neural correlates of performance variability during motor sequence acquisition. NeuroImage. 2012 Mar;60(1):324-31. https://doi.org/10.1016/j.neuroimage.2011.12.049