Monte-Carlo dosimetry simulations of mono- and bi-isotopic radioactive sources used in prostate brachytherapy

Vincent Nuttens, Stephane Lucas

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution


Brachytherapy designs of sources have evolved during the past ten years. However, besides the type of radio-isotope (Pd-103, I-125 and recently Cs-131), no fundamental innovation have been proposed. The present work proposes an original seed loaded with two different isotopes in order to take the advantages of both. Theoretical dosimetry studies by Monte Carlo simulations have been performed to study the dose distribution of a combination of Pd-103 and I-125 in an InterSource-TM seed. It demonstrates advantages in comparison to mono-isotopic sources. Adjusting the relative activity of Pd-103 and I-125, one can get a higher dose at short distance avoiding Pd-103 cold spot and a smaller dose at long distances avoiding I-125 morbidity.
Original languageEnglish
Title of host publicationFifth International Conference on isotopes 5ICI
Subtitle of host publicationProceedings (Brussels, April 25-29 2005)
PublisherMedimond - Monduzzi Editore International Proceedings Division
Number of pages4
ISBN (Print)9788875871864
Publication statusPublished - 2005
Event5th International Conference on Isotopes - Bruxelles, Belgium
Duration: 25 Apr 2005 → …


Conference5th International Conference on Isotopes
Period25/04/05 → …


  • Brachytherapy
  • Multiple radionuclide source
  • Iodine
  • Palladium


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