Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 553-556 |
| Number of pages | 4 |
| Journal | 5th International Conference on Isotopes |
| Publication status | Published - 2005 |
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Keywords
- Brachytherapy
- Multiple radionuclide source
- Iodine
- Palladium
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Monte-Carlo dosimetry simulations of mono- and bi-isotopic radioactive sources used in prostate brachytherapy. / Nuttens, Vincent; Lucas, Stephane.
In: 5th International Conference on Isotopes, 2005, p. 553-556.Research output: Contribution to journal › Literature review
TY - JOUR
T1 - Monte-Carlo dosimetry simulations of mono- and bi-isotopic radioactive sources used in prostate brachytherapy
AU - Nuttens, Vincent
AU - Lucas, Stephane
PY - 2005
Y1 - 2005
N2 - Brachytherapy designs of sources have evolved during the past ten years. However, besides the type of radio-isotope (Pd-103, I-125 and recently Cs-131), no fundamental innovation have been proposed. The present work proposes an original seed loaded with two different isotopes in order to take the advantages of both. Theoretical dosimetry studies by Monte Carlo simulations have been performed to study the dose distribution of a combination of Pd-103 and I-125 in an InterSource-TM seed. It demonstrates advantages in comparison to mono-isotopic sources. Adjusting the relative activity of Pd-103 and I-125, one can get a higher dose at short distance avoiding Pd-103 cold spot and a smaller dose at long distances avoiding I-125 morbidity.
AB - Brachytherapy designs of sources have evolved during the past ten years. However, besides the type of radio-isotope (Pd-103, I-125 and recently Cs-131), no fundamental innovation have been proposed. The present work proposes an original seed loaded with two different isotopes in order to take the advantages of both. Theoretical dosimetry studies by Monte Carlo simulations have been performed to study the dose distribution of a combination of Pd-103 and I-125 in an InterSource-TM seed. It demonstrates advantages in comparison to mono-isotopic sources. Adjusting the relative activity of Pd-103 and I-125, one can get a higher dose at short distance avoiding Pd-103 cold spot and a smaller dose at long distances avoiding I-125 morbidity.
KW - Brachytherapy
KW - Multiple radionuclide source
KW - Iodine
KW - Palladium
M3 - Literature review
SP - 553
EP - 556
JO - 5th International Conference on Isotopes
JF - 5th International Conference on Isotopes
ER -