Low temperature/high pressure polymorphism in dl-cysteine

Vasily S. Minkov, Nikolay A. Tumanov, Raul Quesada Cabrera, Elena V. Boldyreva

Research output: Contribution to journalArticle

30 Downloads (Pure)

Abstract

We compare the response of the crystalline dl-cysteine to cooling and to increasing pressure. The structure undergoes a low-temperature phase transition into an isosymmetric polymorph, dl-cysteine-II, with the conformation of zwitterion changing from gauche- to gauche+. The first pressure-induced transition at 0.1 GPa (the lowest pressure reported for a phase transition in a crystalline amino acid thus far) gives the same polymorph. Further compression of dl-cysteine-II proceeds differently on cooling and with increasing hydrostatic pressure. dl-cysteine-II is preserved down to 3 K, but undergoes phase transitions on compression at about 1.55 GPa, and 6.20 GPa. The changes in the hydrogen bond network preceding the phase transition in dl-cysteine-II in the range 0.25-0.85 GPa differ from those observed on cooling the same structure, but resemble those preceding pressure-induced phase transitions in β- and γ-glycine.

Original languageEnglish
Pages (from-to)2551-2560
Number of pages10
JournalCrystEngComm
Volume12
Issue number9
DOIs
Publication statusPublished - Aug 2010
Externally publishedYes

Fingerprint Dive into the research topics of 'Low temperature/high pressure polymorphism in dl-cysteine'. Together they form a unique fingerprint.

  • Datasets

    CCDC 773688: Experimental Crystal Structure Determination

    Boldyreva, E. V. (Contributor), Cabrera, R. Q. (Contributor), Minkov, V. S. (Contributor) & Tumanov, N. (Contributor), Cambridge Crystallographic Data Centre, 1 Jan 2011

    Dataset

    CCDC 710543: Experimental Crystal Structure Determination

    Bizyaev, S. N. (Contributor), Boldyreva, E. V. (Contributor), Kolesov, B. A. (Contributor), Minkov, V. S. (Contributor) & Tumanov, N. (Contributor), Cambridge Crystallographic Data Centre, 1 Jan 2009

    Dataset

    CCDC 773689: Experimental Crystal Structure Determination

    Boldyreva, E. V. (Contributor), Cabrera, R. Q. (Contributor), Minkov, V. S. (Contributor) & Tumanov, N. (Contributor), Cambridge Crystallographic Data Centre, 1 Jan 2011

    Dataset

    Cite this

    Minkov, V. S., Tumanov, N. A., Cabrera, R. Q., & Boldyreva, E. V. (2010). Low temperature/high pressure polymorphism in dl-cysteine. CrystEngComm, 12(9), 2551-2560. https://doi.org/10.1039/c003617j