Abstract
We compare the response of the crystalline dl-cysteine to cooling and to increasing pressure. The structure undergoes a low-temperature phase transition into an isosymmetric polymorph, dl-cysteine-II, with the conformation of zwitterion changing from gauche- to gauche+. The first pressure-induced transition at 0.1 GPa (the lowest pressure reported for a phase transition in a crystalline amino acid thus far) gives the same polymorph. Further compression of dl-cysteine-II proceeds differently on cooling and with increasing hydrostatic pressure. dl-cysteine-II is preserved down to 3 K, but undergoes phase transitions on compression at about 1.55 GPa, and 6.20 GPa. The changes in the hydrogen bond network preceding the phase transition in dl-cysteine-II in the range 0.25-0.85 GPa differ from those observed on cooling the same structure, but resemble those preceding pressure-induced phase transitions in β- and γ-glycine.
Original language | English |
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Pages (from-to) | 2551-2560 |
Number of pages | 10 |
Journal | CrystEngComm |
Volume | 12 |
Issue number | 9 |
DOIs | |
Publication status | Published - Aug 2010 |
Externally published | Yes |
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Dive into the research topics of 'Low temperature/high pressure polymorphism in dl-cysteine'. Together they form a unique fingerprint.Datasets
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CCDC 773688: Experimental Crystal Structure Determination
Boldyreva, E. V. (Contributor), Cabrera, R. Q. (Contributor), Minkov, V. S. (Contributor) & Tumanov, N. (Contributor), Cambridge Crystallographic Data Centre, 1 Jan 2011
DOI: 10.5517/cctz2pj, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cctz2pj&sid=DataCite
Dataset
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CCDC 710543: Experimental Crystal Structure Determination
Bizyaev, S. N. (Contributor), Boldyreva, E. V. (Contributor), Kolesov, B. A. (Contributor), Minkov, V. S. (Contributor) & Tumanov, N. (Contributor), Cambridge Crystallographic Data Centre, 1 Jan 2009
DOI: 10.5517/ccrvcrp, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccrvcrp&sid=DataCite
Dataset
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CCDC 773689: Experimental Crystal Structure Determination
Boldyreva, E. V. (Contributor), Cabrera, R. Q. (Contributor), Minkov, V. S. (Contributor) & Tumanov, N. (Contributor), Cambridge Crystallographic Data Centre, 1 Jan 2011
DOI: 10.5517/cctz2qk, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cctz2qk&sid=DataCite
Dataset