Long-term in vitro treatment of human glioblastoma cells with temozolomide increases resistance in vivo through up-regulation of GLUT transporter and aldo-keto reductase enzyme AKR1C expression

Benjamin Le Calvé, Michal Rynkowski, Marie Le Mercier, Céline Bruyère, Caroline Lonez, Thierry Gras, Benjamin Haibe-Kains, Gianluca Bontempi, Christine Decaestecker, Jean-Marie Ruysschaert, Robert Kiss, Florence Lefranc

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Biochemistry, Genetics and Molecular Biology