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Abstract
An 18-year-old man was referred to the Internal Medicine ward because of a 2-week history of intermittent high fever, weight loss and cough. Clinical examination revealed hepato-splenomegaly and multiple lymph nodes swelling while laboratory tests showed elevated C-reactive protein, gamma glutamyl transferase and lactate dehydrogenase. All serologic testes for auto-immune antibodies, viruses and bacteria were negative except for Chlamydophila pneumoniae. An 18-FDG PET computed tomography scanner showed hypermetabolism in the liver, spleen and lymph nodes. We therefore conducted a liver biopsy that demonstrated non-necrotizing granulomas. We conclude to a C. pneumoniae infection associated with a granulomatous hepatitis. After treatment with Doxyciclin the patient had no more fever, hepatosplenomegaly resolved and blood testes normalized. This case report is to our knowledge the first report of a granulomatous hepatitis associated with C. pneumoniae respiratory infection.
Original language | English |
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Pages (from-to) | 50-52 |
Number of pages | 3 |
Journal | Acta Clinica Belgica |
Volume | 70 |
Issue number | 1 |
DOIs | |
Publication status | Published - 1 Feb 2015 |
Externally published | Yes |
Keywords
- Chlamydophila pneumoniae
- Doxycycline
- Granulomatosis
- Liver
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