Investigation of mechanism-based thrombin inhibitors: Implications of a highly conserved water molecule for the binding of coumarins within the S pocket

Raphaël Frédérick, Caroline Charlier, Séverine Robert, Johan Wouters, Bernard Masereel, Lionel Pochet

Research output: Contribution to journal › Article › peer-review

2016
Synthesis, evaluation and structure-activity relationship of new 3-carboxamide coumarins as FXIIa inhibitors
Bouckaert, C., Serra, S., Rondelet, G., Dolusic, E., Wouters, J., Dogne, J.-M., Frédérick, R. & Pochet, L., 3 Mar 2016, In: European Journal of Medicinal Chemistry. p. 181-194 14 p., 110.
Research output: Contribution to journal › Article › peer-review
2012
STUDY OF COUMARINS WITH IMPROVED SOLUBILITY TO INHIBIT FXIIa, AN EMERGING TARGET IN THROMBOSIS RESEARCH
Bouckaert, C., Vancraeynest, C., Dolušić, E., Frédérick, R. & Pochet, L., 30 Nov 2012, p. Book of Abstracts, MedChem 2012, Château de Colonster, Liège - November 30, 2012, P01. 1 p.
Research output: Contribution to conference › Poster

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