The cycloaddition of ynamines uith cyclohexenones occurs in the presence of magnesium bromide at the carbonyl but proceeds by attack on the carbon-carbon double bond without catalyst whereas, in contrast, with cyclopentenones, the reaction takes place at the carbon-carbon double bond with or without magnesium bromide.
|Number of pages||4|
|Publication status||Published - 1 Jan 1981|
Ficini, J., Krief, A., Guingant, A., & Desmaele, D. (1981). Influence of magnesium bromide on the regioselectivity of the cycloaddition of ynamines with cyclenones: difference in reactivity between cyclohexenones and cyclopentenones. Tetrahedron Letters, 22(8), 725-728.