In vivo effects of Escherichia coli lipopolysaccharide on regulation of immune response and protein expression in striped catfish (Pangasianodon hypophthalmus)

B.T. Bich Hang, S. Milla, V. Gillardin, P. Kestemont, N.T. Phuong

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Abstract

Lipolysaccharide (LPS), a component of outer membrane protein of gram-negative bacteria, reportedly stimulates fish immune system. However, mechanisms driving this immunomodulatory effect are yet unknown. To determine effects of Escherichia coli lipopolysaccharide on regulation of immune response and protein expression of striped catfish (Pangasianodon hypophthalmus), juvenile fish (20-25. g) were injected with 3, 15 or 45. mg E.coli LPS/kg and challenged with Edwardsiella ictaluri. Plasma cortisol and glucose were rather low and did not differ (p
Original languageEnglish
Pages (from-to)339-347
Number of pages9
JournalFish and Shellfish Immunology
Volume34
Issue number1
DOIs
Publication statusPublished - 1 Jan 2013

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