Abstract
The crystal structure of HEPES [4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid, C8H18N2O4S] is presented. This widely used buffer crystallizes as a zwitterion, the N10 atom of the piperazine ring being the protonation site. The molecules form a network of hydrogen bonds involving both N atoms of the piperazine moiety. The piperazine ring adopts a chair conformation.
| Original language | English |
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| Pages (from-to) | 1687-1688 |
| Number of pages | 2 |
| Journal | Acta crystallographica. Section C: Crystal structure communications |
| Volume | 52 |
| Issue number | 7 |
| Publication status | Published - 15 Jul 1996 |