Health technology assessment in osteoporosis

Mickael Hiligsmann, John A. Kanis, Juliet Compston, Cyrus Cooper, Bruno Flamion, Pierre Bergmann, Jean Jacques Body, Steven Boonen, Olivier Bruyere, Jean Pierre Devogelaer, Stefan Goemaere, Jean Marc Kaufman, Serge Rozenberg, Jean Yves Reginster

Research output: Contribution to journalArticle

Abstract

We review the various aspects of health technology assessment in osteoporosis, including epidemiology and burden of disease, and assessment of the cost-effectiveness of recent advances in the treatment of osteoporosis and the prevention of fracture, in the context of the allocation of health-care resources by decision makers in osteoporosis. This article was prepared on the basis of a symposium held by the Belgian Bone Club and the discussions surrounding that meeting and is based on a review and critical appraisal of the literature. Epidemiological studies confirm the immense burden of osteoporotic fractures for patients and society, with lifetime risks of any fracture of the hip, spine, and forearm of around 40 % for women and 13 % for men. The economic impact is also large; for example, Europe's six largest countries spent €31 billion on osteoporotic fractures in 2010. Moreover, the burden is expected to increase in the future with demographic changes and increasing life expectancy. Recent advances in the management of osteoporosis include novel treatments, better fracture-risk assessment notably via fracture risk algorithms, and improved adherence to medication. Economic evaluation can inform decision makers in health care on the cost-effectiveness of the various interventions. Cost-effectiveness analyses suggest that the recent advances in the prevention and treatment of osteoporosis may constitute an efficient basis for the allocation of scarce health-care resources. In summary, health technology assessment is increasingly used in the field of osteoporosis and could be very useful to help decision makers efficiently allocate health-care resources.

Original languageEnglish
Pages (from-to)1-14
Number of pages14
JournalCalcified Tissue International
Volume93
Issue number1
DOIs
Publication statusPublished - 1 Jul 2013

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Biomedical Technology Assessment
Osteoporosis
Cost-Benefit Analysis
Health Resources
Osteoporotic Fractures
Delivery of Health Care
Cost of Illness
Medication Adherence
Hip Fractures
Life Expectancy
Forearm
Health Care Costs
Epidemiologic Studies
Epidemiology
Spine
Therapeutics
Economics
Demography
Bone and Bones

Keywords

  • Burden of disease
  • Cost-effectiveness
  • Economic evaluation
  • Health technology assessment
  • Osteoporosis

Cite this

Hiligsmann, M., Kanis, J. A., Compston, J., Cooper, C., Flamion, B., Bergmann, P., ... Reginster, J. Y. (2013). Health technology assessment in osteoporosis. Calcified Tissue International, 93(1), 1-14. https://doi.org/10.1007/s00223-013-9724-8
Hiligsmann, Mickael ; Kanis, John A. ; Compston, Juliet ; Cooper, Cyrus ; Flamion, Bruno ; Bergmann, Pierre ; Body, Jean Jacques ; Boonen, Steven ; Bruyere, Olivier ; Devogelaer, Jean Pierre ; Goemaere, Stefan ; Kaufman, Jean Marc ; Rozenberg, Serge ; Reginster, Jean Yves. / Health technology assessment in osteoporosis. In: Calcified Tissue International. 2013 ; Vol. 93, No. 1. pp. 1-14.
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Hiligsmann, M, Kanis, JA, Compston, J, Cooper, C, Flamion, B, Bergmann, P, Body, JJ, Boonen, S, Bruyere, O, Devogelaer, JP, Goemaere, S, Kaufman, JM, Rozenberg, S & Reginster, JY 2013, 'Health technology assessment in osteoporosis', Calcified Tissue International, vol. 93, no. 1, pp. 1-14. https://doi.org/10.1007/s00223-013-9724-8

Health technology assessment in osteoporosis. / Hiligsmann, Mickael; Kanis, John A.; Compston, Juliet; Cooper, Cyrus; Flamion, Bruno; Bergmann, Pierre; Body, Jean Jacques; Boonen, Steven; Bruyere, Olivier; Devogelaer, Jean Pierre; Goemaere, Stefan; Kaufman, Jean Marc; Rozenberg, Serge; Reginster, Jean Yves.

In: Calcified Tissue International, Vol. 93, No. 1, 01.07.2013, p. 1-14.

Research output: Contribution to journalArticle

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AU - Body, Jean Jacques

AU - Boonen, Steven

AU - Bruyere, Olivier

AU - Devogelaer, Jean Pierre

AU - Goemaere, Stefan

AU - Kaufman, Jean Marc

AU - Rozenberg, Serge

AU - Reginster, Jean Yves

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Hiligsmann M, Kanis JA, Compston J, Cooper C, Flamion B, Bergmann P et al. Health technology assessment in osteoporosis. Calcified Tissue International. 2013 Jul 1;93(1):1-14. https://doi.org/10.1007/s00223-013-9724-8